The therapeutic capacity of bone marrow MSC‐derived extracellular vesicles in Achilles tendon healing is passage‐dependent and indicated by specific glycans
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Letters"
DOI: 10.1002/1873-3468.14333
Abstract: The therapeutic potential of mesenchymal stem cell (MSC)‐derived extracellular vesicles (EVs) for various diseases and tissue repair is attracting attention. Here, EVs from conditioned medium of human bone marrow MSCs at passage 5 (P5) and… read more here.
Keywords: tendon healing; achilles tendon; msc; msc evs ... See more keywords
Mesenchymal Stem Cell Exosomes Encapsulated Oral Microcapsules for Acute Colitis Treatment
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Healthcare Materials"
DOI: 10.1002/adhm.202201105
Abstract: Mesenchymal stem cells derived exosomes (MSC‐exos) exhibit an intrinsic and directed efficiency for multiple diseases, while their versatile and effective delivery to the target site is still a challenge. Herein, inspired by the acids and… read more here.
Keywords: oral microcapsules; msc; msc exos; mesenchymal stem ... See more keywords
Scalable Manufacturing of Human Mesenchymal Stromal Cells in the Vertical-Wheel Bioreactor System: An Experimental and Economic Approach.
Sign Up to like & getrecommendations! Published in 2019 at "Biotechnology journal"
DOI: 10.1002/biot.201800716
Abstract: Mesenchymal stromal cells (MSC) hold great promise for tissue engineering applications and cell-based therapies. Large cell doses (>1 × 106 cells kg-1 ) and Good Manufacturing Practices (GMP)-compliant processes are however required for clinical purposes.… read more here.
Keywords: mesenchymal stromal; system; vertical wheel; manufacturing ... See more keywords
Hypoxia preconditioned mesenchymal stem cell-derived exosomes induce ex vivo expansion of umbilical cord blood hematopoietic stem cells CD133+ by stimulation of Notch signalling pathway.
Sign Up to like & getrecommendations! Published in 2021 at "Biotechnology progress"
DOI: 10.1002/btpr.3222
Abstract: Mesenchymal stem cells (MSCs) are crucial cells that play an essential role in the maintenance, self-renewal, and proliferation of hematopoietic stem cells (HSCs) and hematopoietic progenitor cells (HPCs) in the bone marrow niche. It has… read more here.
Keywords: hscs; hematopoietic stem; msc; stem ... See more keywords
Favorable and poor prognosis B‐cell precursor acute lymphoblastic leukemia subtypes reveal distinct leukemic cell properties when interacting with mesenchymal stem cells, differentially modifying their cell stemness and leukemia chemoresistance
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Cell Communication and Signaling"
DOI: 10.1002/ccs3.70009
Abstract: The development of B‐ALL alters the bone marrow microenvironment influencing disease progression and response to therapy. The aggressiveness of particular B‐ALL subtypes could be related to specific mechanisms used to reprogram bone marrow stromal cells.… read more here.
Keywords: msc; mesenchymal stem; prognosis; cell ... See more keywords
Musculin is highly enriched in Th17 and IL‐22‐producing ILC3s and restrains pro‐inflammatory cytokines in murine colitis
Sign Up to like & getrecommendations! Published in 2021 at "European Journal of Immunology"
DOI: 10.1002/eji.202048573
Abstract: The basic helix-loop-helix transcription factor Musculin (MSC, bHLHa22) is found to be highly enriched in pro-inflammatory Th17 cells, with levels correlated with stronger Th17 phenotypes. MSC is also significantly expressed in RORγt+ IL-22-producing group 3… read more here.
Keywords: musculin; highly enriched; colitis; inflammatory cytokines ... See more keywords
Detection of endogenously circulating mesenchymal stem cells in human cancer patients
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Cancer"
DOI: 10.1002/ijc.31727
Abstract: Mesenchymal stem cells (MSCs) can play a vital role in tumor progression and anticancer therapy response, as demonstrated by various in vitro and in vivo model systems. Their ability to home to developing tumors and… read more here.
Keywords: tumor; stem cells; cancer; cancer patients ... See more keywords
Proteomic analysis of MSC‐derived apoptotic vesicles identifies Fas inheritance to ameliorate haemophilia a via activating platelet functions
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Extracellular Vesicles"
DOI: 10.1002/jev2.12240
Abstract: Abstract Apoptotic vesicles (apoVs) are apoptotic cell‐derived nanosized vesicles that play a crucial role in multiple pathophysiological settings. However, their detailed characteristics, specific surface markers, and biological properties are not fully elucidated. In this study,… read more here.
Keywords: apoptotic vesicles; msc; ameliorate haemophilia; msc derived ... See more keywords
SparseCT: System concept and design of multislit collimators.
Sign Up to like & getrecommendations! Published in 2019 at "Medical physics"
DOI: 10.1002/mp.13544
Abstract: PURPOSE SparseCT, an undersampling scheme for compressed sensing (CS) computed tomography (CT), has been proposed to reduce radiation dose by acquiring undersampled projection data from clinical CT scanners (Koesters et al. in, SparseCT: Interrupted-Beam Acquisition and… read more here.
Keywords: undersampling efficiency; beam separation; detector; separation ... See more keywords
The role of ultrasound in enhancing mesenchymal stromal cell‐based therapies
Sign Up to like & getrecommendations! Published in 2020 at "Stem Cells Translational Medicine"
DOI: 10.1002/sctm.19-0391
Abstract: Mesenchymal stromal cells (MSCs) have been a popular platform for cell‐based therapy in regenerative medicine due to their propensity to home to damaged tissue and act as a repository of regenerative molecules that can promote… read more here.
Keywords: medicine; mesenchymal stromal; based therapies; cell based ... See more keywords
Interspecies Incompatibilities Limit the Immunomodulatory Effect of Human Mesenchymal Stromal Cells in the Rat
Sign Up to like & getrecommendations! Published in 2018 at "STEM CELLS"
DOI: 10.1002/stem.2840
Abstract: Mesenchymal stem/stromal cells (MSC) are an immunomodulatory cell population which are under preclinical and clinical investigation for a number of inflammatory conditions including transplantation. In this study, a well‐established rat corneal transplantation model was used… read more here.
Keywords: human msc; stromal cells; effect; msc ... See more keywords