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   Articles with "msc derived" as a keyword



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Proteomic analysis of MSC‐derived apoptotic vesicles identifies Fas inheritance to ameliorate haemophilia a via activating platelet functions

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recommendations! Published in 2022 at "Journal of Extracellular Vesicles"

DOI: 10.1002/jev2.12240

Abstract: Abstract Apoptotic vesicles (apoVs) are apoptotic cell‐derived nanosized vesicles that play a crucial role in multiple pathophysiological settings. However, their detailed characteristics, specific surface markers, and biological properties are not fully elucidated. In this study,… read more here.

Keywords: apoptotic vesicles; msc; ameliorate haemophilia; msc derived ... See more keywords
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Therapeutic Potential of Mesenchymal Stem Cell-Derived Exosomes in the Treatment of Eye Diseases.

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recommendations! Published in 2018 at "Advances in experimental medicine and biology"

DOI: 10.1007/5584_2018_219

Abstract: Mesenchymal stem cells (MSCs) were, due to their immunomodulatory and pro-angiogenic characteristics, extensively explored as new therapeutic agents in cell-based therapy of uveitis, glaucoma, retinal and ocular surface diseases.Since it was recently revealed that exosomes… read more here.

Keywords: treatment eye; therapeutic potential; msc derived; derived exosomes ... See more keywords
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The role and therapeutic potential of MSC-derived exosomes in osteoarthritis.

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recommendations! Published in 2021 at "Archives of biochemistry and biophysics"

DOI: 10.1016/j.abb.2021.109002

Abstract: Osteoarthritis (OA) is the most common painful disease with chronic articular cartilage degeneration. The pathological process of OA is complex and characterized by the imbalance between the synthesis and catabolism of chondrocytes and extracellular matrix,… read more here.

Keywords: role therapeutic; therapeutic potential; msc derived; derived exosomes ... See more keywords
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Recovery of paralyzed limb motor function in canine with complete spinal cord injury following implantation of MSC-derived neural network tissue.

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recommendations! Published in 2018 at "Biomaterials"

DOI: 10.1016/j.biomaterials.2018.07.010

Abstract: We have reported previously that bone marrow mesenchymal stem cell (MSC)-derived neural network scaffold not only survived in the injury/graft site of spinal cord but also served as a "neuronal relay" that was capable of… read more here.

Keywords: network tissue; derived neural; neural network; msc derived ... See more keywords
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hUCB-MSC derived exosomal miR-124 promotes rat liver regeneration after partial hepatectomy via downregulating Foxg1.

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recommendations! Published in 2020 at "Life sciences"

DOI: 10.1016/j.lfs.2020.118821

Abstract: Liver regeneration after partial hepatectomy (PH) is a complex and well-orchestrated process involving multiple factors such as cytokines, growth factors, and signaling pathways. MicroRNAs (miRNAs) participate in various biological processes including liver regeneration after PH.… read more here.

Keywords: liver regeneration; regeneration; msc derived; hucb msc ... See more keywords
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An injectable hydrogel scaffold with IL-1β-activated MSC-derived exosomes for the treatment of endometritis.

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recommendations! Published in 2023 at "Biomaterials science"

DOI: 10.1039/d2bm01586b

Abstract: Chronic endometritis is a common gynecological disease resulting from various long-term recurrent infections, and is closely related to myositis, miscarriage, and even infertility. There is still no satisfactory treatment method currently in clinical therapy. Mesenchymal… read more here.

Keywords: exo pep; hydrogel; msc derived; treatment ... See more keywords
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Therapeutic role of microRNAs of small extracellular vesicles from human mesenchymal stromal/stem cells in the treatment of experimental traumatic brain injury.

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recommendations! Published in 2022 at "Journal of neurotrauma"

DOI: 10.1089/neu.2022.0296

Abstract: Mesenchymal stem/stromal cells (MSC)-derived small extracellular vesicles (sEVs) possess therapeutic potential for treatment of traumatic brain injury (TBI). The essential role of miRNAs underlying the beneficial effects of MSC-derived sEVs for treatment of TBI remains… read more here.

Keywords: sev; ago2; role; vector ... See more keywords
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Extracellular vesicle‐carried microRNA‐27b derived from mesenchymal stem cells accelerates cutaneous wound healing via E3 ubiquitin ligase ITCH

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recommendations! Published in 2020 at "Journal of Cellular and Molecular Medicine"

DOI: 10.1111/jcmm.15692

Abstract: Mesenchymal stem cells (MSCs) have been highlighted as promising candidate cells in relation to cutaneous wound healing. The current study aimed to investigate whether MSC‐derived extracellular vesicles (EVs) could transfer microRNA‐27b (miR‐27b) to influence cutaneous… read more here.

Keywords: itch; wound healing; mesenchymal stem; msc derived ... See more keywords
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Mesenchymal Stem Cells Alleviate Renal Fibrosis and Inhibit Autophagy via Exosome Transfer of miRNA-122a

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recommendations! Published in 2022 at "Stem Cells International"

DOI: 10.1155/2022/1981798

Abstract: Exosomes derived from mesenchymal stem cell (MSC) alleviate kidney damage through autophagy. This study determined whether MSCs relieve renal fibrosis and inhibit autophagy by exosome transfer of miRNA-122a. The gene expression involved in the mTOR… read more here.

Keywords: derived exosomes; renal fibrosis; mirna 122a; msc derived ... See more keywords
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MSC-Derived Extracellular Vesicles Activate Mitophagy to Alleviate Renal Ischemia/Reperfusion Injury via the miR-223-3p/NLRP3 Axis

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recommendations! Published in 2022 at "Stem Cells International"

DOI: 10.1155/2022/6852661

Abstract: Background MSC-derived extracellular vehicles (EVs) exhibit a protective functional role in renal ischemia/reperfusion injury (RIRI). Recent studies have revealed that mitophagy could be a potential target process in the treatment of RIRI. However, whether MSC-derived… read more here.

Keywords: derived evs; mir 223; riri; msc derived ... See more keywords
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Extracellular Vesicles Derived from Wharton’s Jelly Mesenchymal Stem Cells Prevent and Resolve Programmed Cell Death Mediated by Perinatal Hypoxia-Ischemia in Neuronal Cells

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recommendations! Published in 2018 at "Cell Transplantation"

DOI: 10.1177/0963689717738256

Abstract: Hypoxic-ischemic (HI) insult in the perinatal phase harbors a high risk of encephalopathy in the neonate. Brain cells undergo apoptosis, initiating neurodegeneration. So far, therapeutic approaches such as cooling remain limited. Transplantation of mesenchymal stem… read more here.

Keywords: msc derived; cell; hwj msc; microscopy ... See more keywords