Visfatin alters the cytokine and matrix-degrading enzyme profile during osteogenic and adipogenic MSC differentiation.
Sign Up to like & getrecommendations! Published in 2018 at "Osteoarthritis and cartilage"
DOI: 10.1016/j.joca.2018.06.001
Abstract: OBJECTIVES Age-related bone loss is associated with bone marrow adiposity. Adipokines (e.g., visfatin, resistin, leptin) are adipocyte-derived factors with immunomodulatory properties and might influence differentiation of bone marrow-derived mesenchymal stem cells (MSC) in osteoarthritis (OA)… read more here.
Keywords: bone; visfatin; matrix; msc differentiation ... See more keywords
Alterations in chromatin accessibility during osteoblast and adipocyte differentiation in human mesenchymal stem cells
Sign Up to like & getrecommendations! Published in 2022 at "BMC Medical Genomics"
DOI: 10.1186/s12920-022-01168-1
Abstract: Although differential expression of genes is apparent during the adipogenic/osteogenic differentiation of marrow mesenchymal stem cells (MSCs), it is not known whether this is associated with changes in chromosomal structure. In this study, we used… read more here.
Keywords: differentiation; chromatin accessibility; msc differentiation; stem cells ... See more keywords