Practical considerations in transforming MSC therapy for neurological diseases from cell to EV
Sign Up to like & getrecommendations! Published in 2021 at "Experimental neurology"
DOI: 10.1016/j.expneurol.2021.113953
Abstract: Cell-based therapy using Mesenchymal Stromal Cell (MSC) has generally been efficacious in treating a myriad of diseases in animal models and clinical trials. The rationale for MSC therapy was predicated on the potential of MSC… read more here.
Keywords: msc sevs; neurological diseases; msc; therapy ... See more keywords
DOP64 Endoscopically injected allogeneic mesenchymal stromal cells alter the mucosal immune cell compartment in patients with ulcerative proctitis
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Crohn's and Colitis"
DOI: 10.1093/ecco-jcc/jjab073.103
Abstract: Local mesenchymal stromal cell (MSC)-therapy is approved for the treatment of Crohn’s disease-associated perianal fistulas. However, little is known about the working mechanism of local MSC-therapy. For the first time we evaluated engraftment and immunoregulatory… read more here.
Keywords: therapy; msc therapy; local msc; ulcerative proctitis ... See more keywords
MSC therapy in livestock models
Sign Up to like & getrecommendations! Published in 2022 at "Translational Animal Science"
DOI: 10.1093/tas/txac012
Abstract: Abstract Mesenchymal stem cells (MSCs) have great value as therapeutic tools in a wide array of applications in regenerative medicine. The wide repertoire of cell functions regarding tissue regeneration, immunomodulation, and antimicrobial activity makes MSC-based… read more here.
Keywords: msc therapy; based therapy; animal models; therapy ... See more keywords
Translating MSC Therapy in the Age of Obesity
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.943333
Abstract: Mesenchymal stromal cell (MSC) therapy has seen increased attention as a possible option to treat a number of inflammatory conditions including COVID-19 acute respiratory distress syndrome (ARDS). As rates of obesity and metabolic disease continue… read more here.
Keywords: msc therapy; age obesity; therapy; translating msc ... See more keywords
Editorial: Next generation MSC therapy manufacturing, potency and mechanism of action analysis
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2023.1192636
Abstract: COPYRIGHT © 2023 Chinnadurai, Viswanathan and Moll. This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided… read more here.
Keywords: msc therapy; editorial next; generation msc; next generation ... See more keywords
Metabolic Rewiring by Human Placenta-Derived Mesenchymal Stem Cell Therapy Promotes Rejuvenation in Aged Female Rats
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23010566
Abstract: Aging is a degenerative process involving cell function deterioration, leading to altered metabolic pathways, increased metabolite diversity, and dysregulated metabolism. Previously, we reported that human placenta-derived mesenchymal stem cells (hPD-MSCs) have therapeutic effects on ovarian… read more here.
Keywords: msc therapy; human placenta; therapy; rejuvenation ... See more keywords