Exosomes from adipose derived mesenchymal stem cells alleviate diabetic osteoporosis in rats through suppressing NLRP3 inflammasome activation in osteoclasts.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of bioscience and bioengineering"
DOI: 10.1016/j.jbiosc.2021.02.007
Abstract: Inflammation is one of major contributors of diabetic osteoporosis. Adipose derived mesenchymal stem cells (AD-MSCs) show great potential to inhibit inflammation. We investigated the anti-osteoporosis role of AD-MSCs-derived exosomes in diabetic osteoporosis and the underlying… read more here.
Keywords: diabetic osteoporosis; inflammasome activation; mscs derived; nlrp3 inflammasome ... See more keywords
Comparison of the Biological Characteristics of Mesenchymal Stem Cells Derived from the Human Placenta and Umbilical Cord
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-23396-1
Abstract: Mesenchymal stem/stromal cells (MSCs) derived from placental tissue show great therapeutic potential and have been used in medical treatment, but the similarity and differences between the MSCs derived from various parts of the placenta remain… read more here.
Keywords: umbilical cord; mscs derived; mesenchymal stem;
Bone marrow stem cells derived exosomes improve osteoporosis by promoting osteoblast proliferation and inhibiting cell apoptosis.
Sign Up to like & getrecommendations! Published in 2019 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_201902_17014
Abstract: OBJECTIVE The aim of this study was to investigate whether bone marrow stem cells (MSCs) derived exosomes in rats could promote osteoblast proliferation and improve osteoporosis via inhibiting cell apoptosis. MATERIALS AND METHODS MSCs in… read more here.
Keywords: apoptosis; mscs derived; proliferation; cell apoptosis ... See more keywords
MSCs-Derived Exosomes and Neuroinflammation, Neurogenesis and Therapy of Traumatic Brain Injury
Sign Up to like & getrecommendations! Published in 2017 at "Frontiers in Cellular Neuroscience"
DOI: 10.3389/fncel.2017.00055
Abstract: Exosomes are endosomal origin membrane-enclosed small vesicles (30–100 nm) that contain various molecular constituents including proteins, lipids, mRNAs and microRNAs. Accumulating studies demonstrated that exosomes initiated and regulated neuroinflammation, modified neurogenic niches and neurogenesis, and… read more here.
Keywords: therapy traumatic; traumatic brain; derived exosomes; mscs derived ... See more keywords
Prophylactic Evidence of MSCs-Derived Exosomes in Doxorubicin/Trastuzumab-Induced Cardiotoxicity: Beyond Mechanistic Target of NRG-1/Erb Signaling Pathway
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23115967
Abstract: Trastuzumab (Trz) is a humanized monoclonal antibody targeting epidermal growth factor receptor 2 (HER2; ErbB2). The combined administration of Trz and doxorubicin (DOX) has shown potent anti-cancer efficacy; however, this regimen may be accompanied by… read more here.
Keywords: derived exosomes; cardiotoxicity; group; dox trz ... See more keywords