Equine Bone Marrow-Derived MSCs and Their EVs Exhibit Different Immunomodulatory Effects on Cartilage Explants in an In Vitro Osteoarthritis Model.
Sign Up to like & getrecommendations! Published in 2025 at "Cartilage"
DOI: 10.1177/19476035251378693
Abstract: ObjectiveTo compare the effects of equine MSCs and their extracellular vesicles (EV) on stimulated cartilage explants and assess how serum type influences EV production and cartilage inflammation.MethodsEVs were isolated from bone marrow-derived MSCs cultured in… read more here.
Keywords: cartilage explants; derived mscs; mscs evs; cartilage ... See more keywords
Mesenchymal stromal cell-derived extracellular vesicles attenuate lung ischemia-reperfusion injury and enhance reconditioning of donor lungs after circulatory death
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DOI: 10.1186/s12931-017-0704-9
Abstract: BackgroundLung ischemia-reperfusion (IR) injury after transplantation as well as acute shortage of suitable donor lungs are two critical issues impacting lung transplant patients. This study investigates the anti-inflammatory and immunomodulatory role of human mesenchymal stromal… read more here.
Keywords: mscs evs; attenuate lung; ischemia; injury ... See more keywords
The delivery of miR-21a-5p by extracellular vesicles induces microglial polarization via the STAT3 pathway following hypoxia-ischemia in neonatal mice
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DOI: 10.4103/1673-5374.336871
Abstract: Extracellular vesicles (EVs) from mesenchymal stromal cells (MSCs) have previously been shown to protect against brain injury caused by hypoxia-ischemia (HI). The neuroprotective effects have been found to relate to the anti-inflammatory effects of EVs.… read more here.
Keywords: mir 21a; neonatal mice; mscs evs; polarization ... See more keywords