Methylated Septin 9 as a Promising Biomarker in the Diagnosis and Recurrence Monitoring of Colorectal Cancer
Sign Up to like & getrecommendations! Published in 2022 at "Disease Markers"
DOI: 10.1155/2022/7087885
Abstract: Purpose The clinical utility of plasma methylated septin 9 (mSEPT9) DNA in screening and recurrence monitoring for colorectal cancer (CRC) is highly promising. The present study was performed to determine the diagnostic value of mSEPT9… read more here.
Keywords: sensitivity specificity; recurrence; msept9; recurrence monitoring ... See more keywords
Methylated septin 9 gene is an important prognostic marker in stage II and stage III colorectal cancer for evaluating local recurrence or distant metastasis after surgery
Sign Up to like & getrecommendations! Published in 2022 at "BMC Gastroenterology"
DOI: 10.1186/s12876-022-02172-6
Abstract: Background Abnormal hypermethylation of the septin 9 gene was an inchoate incident in some cancers. Though latest several researches had paid attention to its value in prognosis, the consequences were not distinctly, especially in colorectal… read more here.
Keywords: msept9; stage iii; crc patients; stage stage ... See more keywords
The quantitative profiling of blood mSEPT9 determines the detection performance on colorectal tumors.
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DOI: 10.2217/epi-2017-0154
Abstract: AIM To investigate the quantitative relationship between the positive detection rate (PDR) in colorectal tumor detection and the mSEPT9 level. MATERIALS & METHODS The level of blood mSEPT9 in various colorectal diseases was quantified by… read more here.
Keywords: msept9 level; msept9; detection; blood msept9 ... See more keywords
Screening and Prognostic Value of Methylated Septin9 and its Association With Clinicopathological and Molecular Characteristics in Colorectal Cancer
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DOI: 10.3389/fmolb.2021.568818
Abstract: Screening of CRC continues to show poor compliance of endoscopy examination. The detection of mSEPT9 in peripheral blood is among the safe and simple early screening methods for CRC. The issue of how to elucidate… read more here.
Keywords: msept9; detection; prognostic value; peripheral blood ... See more keywords
Clinical value of preoperative methylated septin 9 in Chinese colorectal cancer patients
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DOI: 10.3748/wjg.v25.i17.2099
Abstract: BACKGROUND The methylated septin 9 (mSEPT9) assay was the first blood-based test approved by the United States Food and Drug Administration as a colorectal screening test. However, the diagnostic and prognostic role of preoperative mSEPT9… read more here.
Keywords: msept9; distant metastasis; colorectal cancer; methylated septin ... See more keywords