WRN Helicase: Is There More to MSI-H than Immunotherapy?
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DOI: 10.1158/2159-8290.cd-24-0771
Abstract: In this issue, Picco and colleagues provide further evidence that WRN inhibitors are synthetically lethal in microsatellite instability-high (MSI-H) cancers and function by blocking the helicase domain of select WRN residues. They demonstrate that WRN… read more here.
Keywords: msi immunotherapy; msi; helicase msi; wrn ... See more keywords