Articles with "msi2" as a keyword



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Simultaneous Preparation of High-Purity Silicides, Eutectic Si/MSi2 (M: Nb, Ta, Mo, or W) Alloys, and Silicon through the Separation of Si–M Solvents Using Electromagnetic Directional Crystallization

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Published in 2022 at "Separation and Purification Technology"

DOI: 10.1016/j.seppur.2021.119412

Abstract: Abstract Refractory silicides, eutectic Si/MSi2 (M: Nb, Ta, Mo, or W) alloys, and high-purity silicon are materials that have been used in many high-tech industries. Today, they are prepared using different technologies, i.e., each of… read more here.

Keywords: eutectic msi2; high purity; msi2 alloys; msi2 ... See more keywords
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Musashi RNA-binding protein 2 regulates estrogen receptor 1 function in breast cancer

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Published in 2017 at "Oncogene"

DOI: 10.1038/onc.2016.327

Abstract: Musashi RNA-binding protein 2 (MSI2) has important roles in human cancer. However, the regulatory mechanisms by which MSI2 alters breast cancer pathophysiology have not been clearly identified. Here we demonstrate that MSI2 directly regulates estrogen… read more here.

Keywords: protein; rna binding; msi2; breast cancer ... See more keywords
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Musashi-2 (MSI2) regulates epidermal growth factor receptor (EGFR) expression and response to EGFR inhibitors in EGFR-mutated non-small cell lung cancer (NSCLC)

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Published in 2021 at "Oncogenesis"

DOI: 10.1038/s41389-021-00317-y

Abstract: Non-small cell lung cancer (NSCLC) has limited treatment options. Expression of the RNA-binding protein (RBP) Musashi-2 (MSI2) is elevated in a subset of non-small cell lung cancer (NSCLC) tumors upon progression, and drives NSCLC metastasis.… read more here.

Keywords: egfr; msi2; expression; non small ... See more keywords
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Prognostic value of MSI2 expression in human malignancies: A PRISMA-compliant meta-analysis

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Published in 2022 at "Medicine"

DOI: 10.1097/md.0000000000032064

Abstract: Background: The prognostic value of Musashi-2 (MSI2) in human malignancies remains controversial. We thus conducted this meta-analysis to evaluate the association between MSI2 expression and prognosis of patients with malignancies. Materials and Methods: We searched… read more here.

Keywords: prognostic value; meta analysis; msi2 expression; msi2 ... See more keywords
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Prognostic significance of Musashi 2 (MSI2) RNA-binding protein expression in precancerous polyps and during colorectal cancer (CRC) progression.

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Published in 2020 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2020.38.15_suppl.e16009

Abstract: e16009Background: The RNA-binding protein Musashi-2 (MSI2) controls the translation of proteins that support stem cell identity and lineage determination. Elevated expression of MSI2 plays an impor... read more here.

Keywords: musashi msi2; rna binding; msi2; expression ... See more keywords
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LncRNA DANCR regulates osteosarcoma migration and invasion by targeting miR-149/MSI2 axis.

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Published in 2020 at "European review for medical and pharmacological sciences"

DOI: 10.26355/eurrev_202006_21639

Abstract: OBJECTIVE As a new LncRNA, anti-differentiated non-coding RNA (DANCR) plays an important role in tumorigenesis and development, and its molecular mechanism in osteosarcoma is unclear. In this study, by investigating osteosarcoma tissue and cells, we… read more here.

Keywords: mir 149; msi2; dancr; expression ... See more keywords
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MSI2 deficiency in ILC3s attenuates DSS-induced colitis by affecting the intestinal microbiota

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Published in 2023 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.963379

Abstract: Background The etiology and pathogenesis of inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn’s disease (CD), are generally believed to be related to immune dysfunction and intestinal microbiota disorder. However, the exact mechanism… read more here.

Keywords: intestinal microbiota; microbiota; ilc3s; dss induced ... See more keywords
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Prognostic value of Musashi 2 (MSI2) in cancer patients: A systematic review and meta-analysis

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Published in 2022 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2022.969632

Abstract: Musashi 2 (MSI2) is an RNA-binding protein that regulates mRNA translation of numerous intracellular targets and plays an important role in the development of cancer. However, the prognostic value of MSI2 in various cancers remains… read more here.

Keywords: meta analysis; musashi msi2; cancer patients; msi2 ... See more keywords
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Small Molecule Palmatine Targeting Musashi-2 in Colorectal Cancer

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Published in 2022 at "Frontiers in Pharmacology"

DOI: 10.3389/fphar.2021.793449

Abstract: Musashi-2 (MSI2) is an evolutionally conserved RNA-binding protein and recently considered as an attractive therapeutic target in a wide spectrum of malignancies. However, MSI2-engaged mRNAs are not well profiled, and no MSI2-dependent antagonist is available… read more here.

Keywords: small molecule; molecule palmatine; colorectal cancer; msi2 ... See more keywords