Articles with "msi2" as a keyword



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Simultaneous Preparation of High-Purity Silicides, Eutectic Si/MSi2 (M: Nb, Ta, Mo, or W) Alloys, and Silicon through the Separation of Si–M Solvents Using Electromagnetic Directional Crystallization

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Published in 2022 at "Separation and Purification Technology"

DOI: 10.1016/j.seppur.2021.119412

Abstract: Abstract Refractory silicides, eutectic Si/MSi2 (M: Nb, Ta, Mo, or W) alloys, and high-purity silicon are materials that have been used in many high-tech industries. Today, they are prepared using different technologies, i.e., each of… read more here.

Keywords: eutectic msi2; high purity; msi2 alloys; msi2 ... See more keywords

Musashi RNA-binding protein 2 regulates estrogen receptor 1 function in breast cancer

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Published in 2017 at "Oncogene"

DOI: 10.1038/onc.2016.327

Abstract: Musashi RNA-binding protein 2 (MSI2) has important roles in human cancer. However, the regulatory mechanisms by which MSI2 alters breast cancer pathophysiology have not been clearly identified. Here we demonstrate that MSI2 directly regulates estrogen… read more here.

Keywords: protein; rna binding; msi2; breast cancer ... See more keywords
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Musashi-2 (MSI2) regulates epidermal growth factor receptor (EGFR) expression and response to EGFR inhibitors in EGFR-mutated non-small cell lung cancer (NSCLC)

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Published in 2021 at "Oncogenesis"

DOI: 10.1038/s41389-021-00317-y

Abstract: Non-small cell lung cancer (NSCLC) has limited treatment options. Expression of the RNA-binding protein (RBP) Musashi-2 (MSI2) is elevated in a subset of non-small cell lung cancer (NSCLC) tumors upon progression, and drives NSCLC metastasis.… read more here.

Keywords: egfr; msi2; expression; non small ... See more keywords

Prognostic value of MSI2 expression in human malignancies: A PRISMA-compliant meta-analysis

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Published in 2022 at "Medicine"

DOI: 10.1097/md.0000000000032064

Abstract: Background: The prognostic value of Musashi-2 (MSI2) in human malignancies remains controversial. We thus conducted this meta-analysis to evaluate the association between MSI2 expression and prognosis of patients with malignancies. Materials and Methods: We searched… read more here.

Keywords: prognostic value; meta analysis; msi2 expression; msi2 ... See more keywords

Abstract PR13: Single-cell mapping reveals a common origin for diverse subtypes of pancreatic cancer

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Published in 2024 at "Cancer Research"

DOI: 10.1158/1538-7445.panca2023-pr13

Abstract: The detailed understanding of the molecular basis of tumor initiation and progression is essential for the effective management and treatment of any cancer, including pancreatic cancer. To determine if the stem and progenitor cells can… read more here.

Keywords: cancer; subtypes pancreatic; msi2; single cell ... See more keywords

Uncovering the HOXA9 Translational Regulatory Complex That Promotes AML Leukemic Stem Cells

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Published in 2024 at "Blood"

DOI: 10.1182/blood-2024-211477

Abstract: HOXA9 is a master transcription factor of hematopoiesis and essential for maintaining self-renewal of leukemia stem cells (LSCs). Although mechanisms associated with its transcriptional regulation are extensively studied, how Hoxa9 mRNA translation is controlled remain… read more here.

Keywords: hnrnpc mov10; syncrip; msi2; hoxa9 ... See more keywords

MSI2 regulates NLK-mediated EMT and PI3K/AKT/mTOR pathway to promote pancreatic cancer progression

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Published in 2024 at "Cancer Cell International"

DOI: 10.1186/s12935-024-03444-9

Abstract: The incidence of pancreatic cancer is increasing by years, and the 5-year survival rate is very low. Our team have revealed that Musashi2 (MSI2) could promote aggressive behaviors in pancreatic cancer by downregulating Numb and… read more here.

Keywords: cancer; msi2; akt mtor; emt pi3k ... See more keywords

Prognostic significance of Musashi 2 (MSI2) RNA-binding protein expression in precancerous polyps and during colorectal cancer (CRC) progression.

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Published in 2020 at "Journal of Clinical Oncology"

DOI: 10.1200/jco.2020.38.15_suppl.e16009

Abstract: e16009Background: The RNA-binding protein Musashi-2 (MSI2) controls the translation of proteins that support stem cell identity and lineage determination. Elevated expression of MSI2 plays an impor... read more here.

Keywords: musashi msi2; rna binding; msi2; expression ... See more keywords

LncRNA DANCR regulates osteosarcoma migration and invasion by targeting miR-149/MSI2 axis.

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Published in 2020 at "European review for medical and pharmacological sciences"

DOI: 10.26355/eurrev_202006_21639

Abstract: OBJECTIVE As a new LncRNA, anti-differentiated non-coding RNA (DANCR) plays an important role in tumorigenesis and development, and its molecular mechanism in osteosarcoma is unclear. In this study, by investigating osteosarcoma tissue and cells, we… read more here.

Keywords: mir 149; msi2; dancr; expression ... See more keywords

MSI2 deficiency in ILC3s attenuates DSS-induced colitis by affecting the intestinal microbiota

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Published in 2023 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.963379

Abstract: Background The etiology and pathogenesis of inflammatory bowel disease (IBD), including ulcerative colitis (UC) and Crohn’s disease (CD), are generally believed to be related to immune dysfunction and intestinal microbiota disorder. However, the exact mechanism… read more here.

Keywords: intestinal microbiota; microbiota; ilc3s; dss induced ... See more keywords

Prognostic value of Musashi 2 (MSI2) in cancer patients: A systematic review and meta-analysis

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Published in 2022 at "Frontiers in Oncology"

DOI: 10.3389/fonc.2022.969632

Abstract: Musashi 2 (MSI2) is an RNA-binding protein that regulates mRNA translation of numerous intracellular targets and plays an important role in the development of cancer. However, the prognostic value of MSI2 in various cancers remains… read more here.

Keywords: meta analysis; musashi msi2; cancer patients; msi2 ... See more keywords