Mesothelin-specific CAR-T cell therapy that incorporates an HLA-gated safety mechanism selectively kills tumor cells
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DOI: 10.1136/jitc-2021-003826
Abstract: Background Mesothelin (MSLN) is a classic tumor-associated antigen that is expressed in lung cancer and many other solid tumors. However, MSLN is also expressed in normal mesothelium which creates a significant risk of serious inflammation… read more here.
Keywords: msln car; tmod; car; msln ... See more keywords