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Unveiling the Biosynthetic Pathway for Short Mycolic Acids in Nontuberculous Mycobacteria: Mycobacterium smegmatis MSMEG_4301 and Its Ortholog Mycobacterium abscessus MAB_1915 Are Essential for the Synthesis of α′-Mycolic Acids

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Published in 2022 at "Microbiology Spectrum"

DOI: 10.1128/spectrum.01288-22

Abstract: Mycobacterium abscessus is a nontuberculous mycobacterium responsible for an increasing number of hard-to-treat infections due to the impervious nature of its cell envelope, a natural barrier to several antibiotics. Mycolic acids are key components of… read more here.

Keywords: mycolic acids; mycobacterium abscessus; synthesis; mycobacterium ... See more keywords