An Adjustable pH-Responsive Drug Delivery System Based on Self-Assembly Polypeptide-Modified Mesoporous Silica.
Sign Up to like & getrecommendations! Published in 2020 at "Macromolecular bioscience"
DOI: 10.1002/mabi.202000034
Abstract: In this study, an adjustable pH-responsive drug delivery system using mesoporous silica nanoparticles (MSNs) as the host materials and the modified polypeptides as the nanovalves is reported. Since the polypeptide can self-assemble via electrostatic interaction… read more here.
Keywords: mesoporous silica; msn; drug; adjustable responsive ... See more keywords
YSA-conjugated mesoporous silica nanoparticles effectively target EphA2-overexpressing breast cancer cells
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Chemotherapy and Pharmacology"
DOI: 10.1007/s00280-018-3535-6
Abstract: PurposeNeoadjuvant chemotherapy is commonly used to treat patients with locally advanced breast cancer and a common option for primary operable disease. However, systemic toxicity including cardiotoxicity and inefficient delivery are significant challenges form any chemotherapeutics.… read more here.
Keywords: delivery; msn; breast cancer; cancer cells ... See more keywords
Exploring the role of mesoporous silica nanoparticle in the development of novel drug delivery systems.
Sign Up to like & getrecommendations! Published in 2021 at "Drug delivery and translational research"
DOI: 10.1007/s13346-021-00935-4
Abstract: The biocompatible nature of mesoporous silica nanoparticles (MSN) attracted researchers' attention to deliver therapeutic agents in the treatment of various diseases, where their porous nature, high drug loading efficiency, and suitability to functionalize with a… read more here.
Keywords: drug delivery; mesoporous silica; delivery systems; msn ... See more keywords
Applications of mesoporous silica in biosensing and controlled release of insulin
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Pharmaceutics"
DOI: 10.1016/j.ijpharm.2018.07.037
Abstract: Graphical abstract Figure. No Caption available. Abstract The development of new oral insulin delivery systems could bring significant benefits to insulin‐dependent patients due to the simplicity of the method, avoidance of pain caused by parenteral… read more here.
Keywords: insulin; controlled release; mesoporous silica; msn ... See more keywords
How to Protect Our Largest Organ: Perioperative Skin Impairment Initiative
Sign Up to like & getrecommendations! Published in 2018 at "Journal of PeriAnesthesia Nursing"
DOI: 10.1016/j.jopan.2018.06.020
Abstract: Team Leader: Terry Kohlleppel RN BSN OCN University of Texas at MD Anderson Cancer Center, Houston, Texas Team Members: Staci Eguia MSN RN CCRN, Cori Kopecki MSN RN OCN, Kim Kitchen MSN RN, LIlibeth Dequito… read more here.
Keywords: protect largest; bsn; largest organ; msn ... See more keywords
The Misshapen kinase regulates the size and stability of the germline ring canals in the Drosophila egg chamber.
Sign Up to like & getrecommendations! Published in 2018 at "Developmental biology"
DOI: 10.1016/j.ydbio.2018.05.006
Abstract: Intercellular bridges are conserved structures that allow neighboring cells to exchange cytoplasmic material; defects in intercellular bridges can lead to infertility in many organisms. Here, we use the Drosophila egg chamber to study the mechanisms… read more here.
Keywords: egg chamber; germline ring; msn; size ... See more keywords
Thermosensitive PNIPAM-Based Hydrogel Crosslinked by Composite Nanoparticles as Rapid Wound-Healing Dressings.
Sign Up to like & getrecommendations! Published in 2023 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.2c01380
Abstract: Chronic wounds are prone to produce excessive reactive oxygen species (ROS), which are the main reason for multiple bacterial infections and ulcers at the wound. Therefore, regulating ROS is the key in the process of… read more here.
Keywords: wound healing; msn; hydrogel; pnipam based ... See more keywords
Development of Proanthocyanidin-Loaded Mesoporous Silica Nanoparticles for Improving Dental Adhesion
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.2c00728
Abstract: Dentin biomodification is a promising approach to enhance dental tissue biomechanics and biostability for restorative and reparative therapies. One of the most active dentin tissue biomodifiers is proanthocyanidin (PAC)-rich natural extracts, which are used in… read more here.
Keywords: msn; silica nanoparticles; loaded pac; mesoporous silica ... See more keywords
An MSN-PEG-IP drug delivery system and IL13Rα2 as targeted therapy for glioma.
Sign Up to like & getrecommendations! Published in 2017 at "Nanoscale"
DOI: 10.1039/c6nr08786h
Abstract: A combination of gene therapy and chemotherapy has recently received interest as a targeted therapy for glioma. A mesoporous silica nanoparticle (MSN)-based vehicle coated with IL13Rα2-targeted peptide (IP) using polyethylene glycol (PEG), MSN-PEG-IP (MPI), was… read more here.
Keywords: il13r; glioma; targeted therapy; msn ... See more keywords
Development of arginine based nanocarriers for targeting and treatment of intracellular Salmonella
Sign Up to like & getrecommendations! Published in 2017 at "RSC Advances"
DOI: 10.1039/c6ra27868j
Abstract: Arginine decorated nanocarriers exhibited intravacuolar targeting capability which was utilized to deliver antibiotics into the intracellular niche of pathogens like Salmonella and Mycobacterium. The arginine based nanocarrier system (Arg-MSN) was developed on a mesoporous silica… read more here.
Keywords: arginine based; salmonella; msn; arg msn ... See more keywords
Succinylated casein-coated peptide-mesoporous silica nanoparticles as an antibiotic against intestinal bacterial infection.
Sign Up to like & getrecommendations! Published in 2019 at "Biomaterials science"
DOI: 10.1039/c9bm00003h
Abstract: Increasing drug resistance necessitates the discovery of novel bactericides. Human defensin (HD) peptides can eliminate resistant bacteria and are promising candidates for next-generation antibiotics. T7E21R-HD5 is a potent bactericide designed by site mutations at enteric… read more here.
Keywords: t7e21r; mesoporous silica; msn; t7e21r hd5 ... See more keywords