GABAA receptor activation modulates the muscle sympathetic nerve activity responses at the onset of static exercise in humans.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of applied physiology"
DOI: 10.1152/japplphysiol.00423.2021
Abstract: Exercise is a well-known sympathoexcitatory stimulus. However, muscle sympathetic nerve activity (MSNA) can decrease during the onset of muscle contraction. Yet, the underlying mechanisms and neurotransmitters involved in the sympathetic responses at the onset of… read more here.
Keywords: responses onset; heart; msna; onset static ... See more keywords
Endothelin-1 receptor blockade does not alter the sympathetic and hemodynamic response to acute intermittent hypoxia in men.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of applied physiology"
DOI: 10.1152/japplphysiol.00837.2021
Abstract: Repeat exposures to low oxygen (intermittent hypoxia, IH), like that observed in sleep apnea, elicit increases in muscle sympathetic nerve activity (MSNA) and blood pressure (BP) in men. Endothelin (ET) receptor antagonists can attenuate the… read more here.
Keywords: receptor; endothelin receptor; msna; intermittent hypoxia ... See more keywords
Attenuated Sympathetic Blood Pressure Transduction in Patients With Treated Heart Failure With Reduced Ejection Fraction
Sign Up to like & getrecommendations! Published in 2022 at "Hypertension"
DOI: 10.1161/hypertensionaha.122.19850
Abstract: Background: Heart failure with reduced ejection fraction (HFrEF) is associated with reduced cardiac β-adrenergic signal transduction in response to chronic elevations in neurally released and circulating norepinephrine. Whether elevations in muscle sympathetic nerve activity (MSNA)… read more here.
Keywords: patients hfref; ejection fraction; transduction; heart ... See more keywords
Muscle Metaboreflex Control of Sympathetic Activity Is Preserved following Acute Intermittent Hypercapnic Hypoxia.
Sign Up to like & getrecommendations! Published in 2021 at "Medicine and science in sports and exercise"
DOI: 10.1249/mss.0000000000002716
Abstract: PURPOSE In normotensive patients with OSA, the muscle sympathetic nerve activity (MSNA) response to exercise is increased while metaboreflex control of MSNA is decreased. We tested the hypotheses that acute intermittent hypercapnic hypoxia (IHH) in… read more here.
Keywords: ihh; metaboreflex control; msna; activity ... See more keywords
Neurovascular control during exercise in acute coronary syndrome patients with Gln27Glu polymorphism of β2-adrenergic receptor
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DOI: 10.1371/journal.pone.0173061
Abstract: Background Gln27Glu (rs1042714) polymorphism of the β2-adrenergic receptor (ADRB2) has been association with cardiovascular functionality in healthy subjects. However, it is unknown whether the presence of the ADRB2 Gln27Glu polymorphism influences neurovascular responses during exercise… read more here.
Keywords: msna; gln27glu polymorphism; exercise; gln27glu glu27glu ... See more keywords
Identifying Increases in Activity of the Human RVLM Through MSNA-Coupled fMRI
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Neuroscience"
DOI: 10.3389/fnins.2019.01369
Abstract: Aim We initially developed concurrent recording of muscle sympathetic nerve activity (MSNA) and functional magnetic resonance imaging (fMRI) of the brain to functionally identify the human homolog of the rostral ventrolateral medulla (RVLM). Here we… read more here.
Keywords: coupled fmri; msna; signal intensity; msna coupled ... See more keywords