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Early differences in membrane properties at the neuromuscular junctions of ALS model mice: Effects of 25-hydroxycholesterol.

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Published in 2021 at "Life sciences"

DOI: 10.1016/j.lfs.2021.119300

Abstract: AIMS Plasma hyperlipidemia is a protective factor in amyotrophic lateral sclerosis (ALS) while cholesterol-lowering drugs aggravate the pathology. We hypothesize that this phenomenon can be linked with membrane lipid alterations in the neuromuscular junctions (NMJs)… read more here.

Keywords: raft; membrane properties; ceramide; neuromuscular junctions ... See more keywords