Peroxidase-Mimicking Nanoassembly Mitigates Lipopolysaccharide-Induced Endotoxemia and Cognitive Damage in the Brain by Impeding Inflammatory Signaling in Macrophages.
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DOI: 10.1021/acs.nanolett.8b02785
Abstract: Oxidative stress during sepsis pathogenesis remains the most-important factor creating imbalance and dysregulation in immune-cell function, usually observed following initial infection. Hydrogen peroxide (H2O2), a potentially toxic reactive oxygen species (ROS), is excessively produced by… read more here.
Keywords: mspam; mspam nanoassembly; inflammatory; induced endotoxemia ... See more keywords