Articles with "msr1" as a keyword



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Comprehensive analysis of the prognostic and role in immune cell infiltration of MSR1 expression in lower-grade gliomas.

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Published in 2022 at "Cancer medicine"

DOI: 10.1002/cam4.4603

Abstract: BACKGROUND The therapeutic effects of conventional treatment on gliomas are not promising. The tumor microenvironment (TME) has a close association with the invasiveness of multiple types of tumors, including low-grade gliomas (LGG). This study aims… read more here.

Keywords: analysis; expression; msr1; lgg patients ... See more keywords
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Macrophage Scavenger Receptor 1 mediates lipid-induced inflammation in non-alcoholic fatty liver disease.

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Published in 2021 at "Journal of hepatology"

DOI: 10.1016/j.jhep.2021.12.012

Abstract: BACKGROUND & AIMS Obesity-associated inflammation is a key player in the pathogenesis of non-alcoholic fatty liver disease (NAFLD). However, the role of macrophage scavenger receptor 1 (MSR1, CD204) remains incompletely understood. METHODS 170 NAFLD liver… read more here.

Keywords: non alcoholic; macrophage; msr1; disease ... See more keywords
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Sirt6 deletion in bone marrow-derived cells increases atherosclerosis - Central role of macrophage scavenger receptor 1.

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Published in 2020 at "Journal of molecular and cellular cardiology"

DOI: 10.1016/j.yjmcc.2020.01.002

Abstract: AIMS Sirtuin 6 (Sirt6) is a NAD+-dependent deacetylase that plays a key role in DNA repair, inflammation and lipid regulation. Sirt6-null mice show severe metabolic defects and accelerated aging. Macrophage-foam cell formation via scavenger receptors… read more here.

Keywords: msr1; bone; role; sirt6 ... See more keywords
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Comprehensive analysis of immune cell infiltration and role of MSR1 expression in aneurysmal subarachnoid haemorrhage.

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Published in 2022 at "Cell proliferation"

DOI: 10.1111/cpr.13379

Abstract: Aneurysmal subarachnoid haemorrhage (aSAH), resulting from the rupture of intracranial aneurysms, can yield high mortality and disability. This study aimed to explore the immune infiltration of aneurysmal tissues and investigate a novel mechanism underlying aSAH.… read more here.

Keywords: infiltration; aneurysmal subarachnoid; analysis; msr1 ... See more keywords

Activation of RARα Receptor Attenuates Neuroinflammation After SAH via Promoting M1-to-M2 Phenotypic Polarization of Microglia and Regulating Mafb/Msr1/PI3K-Akt/NF-κB Pathway

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Published in 2022 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.839796

Abstract: Background and Purpose Subarachnoid hemorrhage (SAH) is a life-threatening subtype of stroke with high rates of mortality. In the early stages of SAH, neuroinflammation is one of the important mechanisms leading to brain injury after… read more here.

Keywords: rar receptor; activation; msr1; activation rar ... See more keywords