A MST1–FOXO1 cascade establishes endothelial tip cell polarity and facilitates sprouting angiogenesis
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DOI: 10.1038/s41467-019-08773-2
Abstract: Hypoxia is a main driver of sprouting angiogenesis, but how tip endothelial cells are directed to hypoxic regions remains poorly understood. Here, we show that an endothelial MST1–FOXO1 cascade is essential for directional migration of… read more here.
Keywords: foxo1 cascade; tip; mst1 foxo1; sprouting angiogenesis ... See more keywords