Lin28a protects against diabetic cardiomyopathy through Mst1 inhibition
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.29321
Abstract: Lin28a has been found to enhance glucose uptake and insulin sensitivity. Lin28a alleviates cardiac dysfunction under various pathological conditions. However, the effects and underlying mechanisms of Lin28a on diabetic cardiomyopathy (DCM) are not well‐understood. The… read more here.
Keywords: mst1; mst1 inhibition; high glucose; lin28a ... See more keywords
Mammalian Ste20-like kinase 1 inhibition as a cellular mediator of anoikis in mouse bone marrow mesenchymal stem cells
Sign Up to like & getrecommendations! Published in 2023 at "World Journal of Stem Cells"
DOI: 10.4252/wjsc.v15.i3.90
Abstract: BACKGROUND The low survival rate of mesenchymal stem cells (MSCs) caused by anoikis, a form of apoptosis, limits the therapeutic efficacy of MSCs. As a proapoptotic molecule, mammalian Ste20-like kinase 1 (Mst1) can increase the… read more here.
Keywords: inhibition; mst1 inhibition; expression; anoikis ... See more keywords