MST4 as a novel therapeutic target for autophagy and radiosensitivity in gastric cancer
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DOI: 10.1002/iub.2682
Abstract: Mammalian ste20‐like kinase 4 (MST4) and autophagy have been implicated in ailments such as inflammatory and cancers. read more here.
Keywords: therapeutic target; mst4 novel; novel therapeutic; autophagy radiosensitivity ... See more keywords
MicroRNA-486-5p inhibits ovarian granulosa cell proliferation and participates in the development of PCOS via targeting MST4.
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DOI: 10.26355/eurrev_201909_18823
Abstract: Objective To explore whether microRNA-486-5p affected the proliferation of ovarian granulosa cells by targeting MST4 (silk/threonine protein kinase 4), thereby promoting the development of polycystic ovary syndrome (PCOS). Materials and methods The level of microRNA-486-5p… read more here.
Keywords: cycle; cell proliferation; mst4; cell ... See more keywords
MST4 negatively regulates the EMT, invasion and metastasis of HCC cells by inactivating PI3K/AKT/Snail1 axis
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DOI: 10.7150/jca.60008
Abstract: Background: Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide and has a poor prognosis due to the high incidence of invasion and metastasis-related progression. However, the underlying mechanism remains elusive, and valuable… read more here.
Keywords: mst4; hcc; invasion; snail1 ... See more keywords