CRISPR/Cas9‐mediated sheep MSTN gene knockout and promote sSMSCs differentiation
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.27474
Abstract: Myostatin (MSTN) is an important gene involved in the regulation of embryonic muscle cells and adult muscle development; it has a good application prospect in transgenic animal production by improving the yield of muscle. The… read more here.
Keywords: mstn gene; mstn; crispr cas9; gene knockout ... See more keywords
Muscle growth in targeted knockout common carp (Cyprinus carpio) mstn gene with low off-target effects
Sign Up to like & getrecommendations! Published in 2022 at "Aquaculture"
DOI: 10.1016/j.aquaculture.2021.737423
Abstract: Abstract The gene mstn is a negative regulator of skeletal muscle growth and development in vertebrates, including teleosts. Common carp (Cyprinus carpio) is an economically important food fish, and an increase in its skeletal muscle… read more here.
Keywords: mstn gene; common carp; gene; growth ... See more keywords
Production of MSTN Gene-Edited Embryos of Buffalo Using the CRISPR/Cas9 System and SCNT.
Sign Up to like & getrecommendations! Published in 2023 at "Cellular reprogramming"
DOI: 10.1089/cell.2023.0003
Abstract: The clustered regularly interspaced short palindromic repeats (CRISPR)/Cas9 system and somatic cell nuclear transfer (SCNT) have been used to produce genome-edited farm animal species for improved production and health traits; however, these tools are rarely… read more here.
Keywords: crispr cas9; mstn gene; buffalo; cas9 system ... See more keywords
Association of MSTN gene polymorphism (C354T) with performance traits in raccoon dogs
Sign Up to like & getrecommendations! Published in 2018 at "Canadian Journal of Animal Science"
DOI: 10.1139/cjas-2017-0070
Abstract: Abstract: The aim of the study was to identify polymorphisms within nuclear DNA genes and determine their association with the performance traits of farmed raccoon dogs. The study involved 354 animals and their breeding documentation… read more here.
Keywords: mstn gene; association; raccoon dogs; performance ... See more keywords
Myostatin gene role in regulating traits of poultry species for potential industrial applications
Sign Up to like & getrecommendations! Published in 2024 at "Journal of Animal Science and Biotechnology"
DOI: 10.1186/s40104-024-01040-5
Abstract: The myostatin ( MSTN ) gene is considered a potential genetic marker to improve economically important traits in livestock, since the discovery of its function using the MSTN knockout mice. The anti-myogenic function of the… read more here.
Keywords: function; poultry species; mstn gene; gene ... See more keywords
Comparison of Microbial Community and Metabolites in Four Stomach Compartments of Myostatin-Gene-Edited and Non-edited Cattle
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2022.844962
Abstract: Myostatin (MSTN), a major negative regulator of skeletal muscle mass and an endocrine factor, can regulate the metabolism of various organisms. Inhibition of the MSTN gene can improve meat production from livestock. Rumen microorganisms are… read more here.
Keywords: stomach compartments; four stomach; edited cattle; mstn gene ... See more keywords
An Antisense Oligonucleotide against a Splicing Enhancer Sequence within Exon 1 of the MSTN Gene Inhibits Pre-mRNA Maturation to Act as a Novel Myostatin Inhibitor
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23095016
Abstract: Antisense oligonucleotides (ASOs) are agents that modulate gene function. ASO-mediated out-of-frame exon skipping has been employed to suppress gene function. Myostatin, encoded by the MSTN gene, is a potent negative regulator of skeletal muscle growth.… read more here.
Keywords: exon mstn; maturation; pre mrna; mstn gene ... See more keywords