Articles with "msx1" as a keyword



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Prmt1 regulates craniofacial bone formation upstream of Msx1

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Published in 2018 at "Mechanisms of Development"

DOI: 10.1016/j.mod.2018.05.001

Abstract: Protein arginine methylation has been recently identified as an important form of post-translational modification (PTM). It is carried out by the protein arginine methyltransferase (PRMT) family of enzymes, which in mammals consists of nine members.… read more here.

Keywords: msx1; craniofacial bone; formation; prmt1 ... See more keywords
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Establishment of a congenital tooth agenesis related gene MSX1 knockout human embryonic stem cell lines by CRISPR-Cas9 technology.

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Published in 2017 at "Stem cell research"

DOI: 10.1016/j.scr.2017.05.008

Abstract: Human MSX1 gene is mapped to chromosome 4 and encodes a 303aa homeobox protein MSX1. MSX1 expression appears during early tooth development of vertebrate embryogenesis. Mutations in this protein are related to human tooth anomalie,… read more here.

Keywords: knockout human; cell lines; msx1; stem ... See more keywords
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RNA Profiling of the Human and Mouse Spinal Cord Stem Cell Niches Reveals an Embryonic-like Regionalization with MSX1+ Roof-Plate-Derived Cells

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Published in 2019 at "Stem Cell Reports"

DOI: 10.1016/j.stemcr.2019.04.001

Abstract: Summary Anamniotes, rodents, and young humans maintain neural stem cells in the ependymal zone (EZ) around the central canal of the spinal cord, representing a possible endogenous source for repair in mammalian lesions. Cell diversity… read more here.

Keywords: cord; msx1; rna profiling; embryonic like ... See more keywords

Study of rs12532, rs8670 Polymorphism of Msh Homeobox 1 (MSX1), rs61754301, rs4904155 Polymorphism of Paired Box Gene 9 (PAX9), and rs2240308 Polymorphism of Axis Inhibitor Protein 2 (AXIN2) Genes in Nonsyndromic Hypodontia

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Published in 2019 at "BioMed Research International"

DOI: 10.1155/2019/2183720

Abstract: The etiology of hypodontia is complex, in which both genetic and environmental factors can be related. The main objective of our study was to contribute to elucidating the genetic background of nonsyndromic hypodontia (NSH). In… read more here.

Keywords: agenesis; hypodontia; msx1; study ... See more keywords
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MSX1 Drives Tooth Morphogenesis Through Controlling Wnt Signaling Activity

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Published in 2022 at "Journal of Dental Research"

DOI: 10.1177/00220345211070583

Abstract: Tooth agenesis is a common structural birth defect in humans that results from failure of morphogenesis during early tooth development. The homeobox transcription factor Msx1 and the canonical Wnt signaling pathway are essential for “bud… read more here.

Keywords: morphogenesis; dkk2; tooth development; wnt signaling ... See more keywords