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Published in 2019 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.27169
Abstract: Multidrug‐resistant Mycobacterium tuberculosis (Mtb) has emerged as a major health challenge, necessitating the search for new molecular targets. A secretory amidohydrolase, l‐asparaginase of Mtb (MtA), originally implicated in nitrogen assimilation and neutralization of acidic microenvironment…
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Keywords:
mycobacterium tuberculosis;
mta;
target;
active site ... See more keywords
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Published in 2020 at "Clinical Oral Investigations"
DOI: 10.1007/s00784-020-03507-x
Abstract: (1) To evaluate the effectiveness of the static-guided (SG) endodontics technique for accessing the root canal through the mineral trioxide aggregate (MTA) and (2) to evaluate the effect of this technique on the fracture strength…
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Keywords:
technique;
mta;
group;
fracture strength ... See more keywords
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Published in 2020 at "Bioactive Materials"
DOI: 10.1016/j.bioactmat.2020.04.001
Abstract: Addition of zinc oxide (ZnO) to Mineral Trioxide Aggregate (MTA) has been shown to rectify tooth discoloration caused by Angelus MTA. This study evaluated the microhardness, compressive strength, calcium ion release and crystalline structures of…
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Keywords:
proroot mta;
mta;
compressive strength;
environmental conditions ... See more keywords
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Published in 2020 at "Fuel"
DOI: 10.1016/j.fuel.2020.117204
Abstract: Abstract Methanol to aromatics (MTA) following dual cycles concept unavoidably produced considerable amounts of olefinic intermediates and paraffinic by-products. Their formation and further conversion were vital to improving aromatics production. In this study, a two-stage fluid…
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Keywords:
temperature;
secondary conversion;
mta;
conversion ... See more keywords
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1
Published in 2017 at "Journal of dentistry"
DOI: 10.1016/j.jdent.2017.08.018
Abstract: OBJECTIVE To compare the effect of QMix (Dentsply Sirona), 7% maleic acid (MA), and 17% ethylenediaminetetraacetic acid (EDTA) on the microhardness, flexural strength and microstructure of mineral trioxide aggregate (MTA; ProRoot MTA, Dentsply Sirona). METHODS…
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Keywords:
flexural strength;
physical properties;
distilled water;
mta ... See more keywords
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Published in 2019 at "Journal of the Formosan Medical Association = Taiwan yi zhi"
DOI: 10.1016/j.jfma.2019.07.010
Abstract: BACKGROUND/PURPOSE Mineral trioxide aggregate (Pro-Root MTA, PR-MTA) and bioceramics (iRoot® SP Injectable Root Canal Sealer, iR-BC) are used for making apical plugs used in apexification, repairing root perforations during root canal therapy, and treating internal…
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Keywords:
raw 264;
mineral trioxide;
mta;
mta induced ... See more keywords
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Published in 2017 at "Journal of Endodontics"
DOI: 10.1016/j.joen.2016.12.013
Abstract: Introduction: Mineral trioxide aggregate (MTA) regulates bone remodeling, particularly osteoclast differentiation. However, intracellular mechanisms underlying the anti‐osteoclastogenesis of MTA remain unclear. This study aimed to evaluate the potential alterations of autophagic pathway during anti‐osteoclastogenic effects…
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Keywords:
trioxide aggregate;
autophagic pathway;
mta;
mta extracts ... See more keywords
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Published in 2018 at "Journal of Endodontics"
DOI: 10.1016/j.joen.2018.07.017
Abstract: Introduction: Elastinlike polypeptide (ELP) is 1 of the genetically engineered, protein‐based polypeptides, which offers outstanding advantages such as superior biocompatibility, long‐term stability, elasticity, and cost‐effectiveness. This study aimed to investigate the effect of an ELP‐based…
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Keywords:
mta;
physical properties;
matrix physical;
based matrix ... See more keywords
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1
Published in 2022 at "Journal of pediatric urology"
DOI: 10.1016/j.jpurol.2022.02.003
Abstract: INTRODUCTION Enuresis prevalence is approximately 5-15% in children aged 6-7 years. The presence of attention deficit hyperactivity disorder (ADHD) in enuretic children is associated with 3 times greater risk of persistent enuresis. The Multimodal Treatment…
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Keywords:
enuresis;
mta snap;
adhd symptoms;
enuretic population ... See more keywords
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Published in 2024 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.4c00133
Abstract: It has been shown that PRMT5 inhibition by small molecules can selectively kill cancer cells with homozygous deletion of the MTAP gene if the inhibitors can leverage the consequence of MTAP deletion, namely, accumulation of…
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Keywords:
brain;
discovery tng908;
mtap deleted;
mta ... See more keywords
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Published in 2025 at "Journal of Medicinal Chemistry"
DOI: 10.1021/acs.jmedchem.4c03101
Abstract: Inhibition of the methyltransferase enzyme PRMT5 by MTA accumulation is a vulnerability of MTAP-deleted cancers. Herein, we report the discovery and optimization of a quinolin-2-amine DEL hit that cooperatively binds PRMT5:MEP50 and MTA to generate…
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Keywords:
library screening;
mta;
dna encoded;
prmt5 ... See more keywords