Synthesis and antimycobacterial activity of triterpeni≿ A-ring azepanes.
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DOI: 10.1016/j.ejmech.2017.11.035
Abstract: A series of A-ring azepanones and azepanes derived from betulonic, oleanonic and ursonic acids was synthesized and evaluated for their in vitro antimycobacterial activities against M. tuberculosis (MTB) H37Rv and SDR-TB in the National Institute of Allergy… read more here.
Keywords: antimycobacterial activity; mtb h37rv; activity triterpeni; triterpeni ring ... See more keywords
In Silico Identification of Novel Derivatives of Rifampicin Targeting Ribonuclease VapC2 of M. tuberculosis H37Rv: Rifampicin Derivatives Target VapC2 of Mtb H37Rv
Sign Up to like & getrecommendations! Published in 2023 at "Molecules"
DOI: 10.3390/molecules28041652
Abstract: The emergence of multi-drug-resistant Mycobacterium tuberculosis (Mtb) strains has rendered many of the currently available anti-TB drugs ineffective. Hence, there is a pressing need to discover new potential drug targets/candidates. In this study, attempts have… read more here.
Keywords: ribonuclease vapc2; h37rv; mtb h37rv; rif ... See more keywords