B Cells Producing Type I IFN Modulate Macrophage Polarization in Tuberculosis
Sign Up to like & getrecommendations! Published in 2018 at "American Journal of Respiratory and Critical Care Medicine"
DOI: 10.1164/rccm.201707-1475oc
Abstract: Rationale: In addition to their well‐known function as antibody‐producing cells, B lymphocytes can markedly influence the course of infectious or noninfectious diseases via antibody‐independent mechanisms. In tuberculosis (TB), B cells accumulate in lungs, yet their… read more here.
Keywords: macrophage polarization; mtb infected; ifn; type ifn ... See more keywords
IL-22 produced by type 3 innate lymphoid cells (ILC3s) reduces the mortality of type 2 diabetes mellitus (T2DM) mice infected with Mycobacterium tuberculosis
Sign Up to like & getrecommendations! Published in 2019 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1008140
Abstract: Previously, we found that pathological immune responses enhance the mortality rate of Mycobacterium tuberculosis (Mtb)-infected mice with type 2 diabetes mellitus (T2DM). In the current study, we evaluated the role of the cytokine IL-22 (known… read more here.
Keywords: mice infected; t2dm mice; mtb infected; mortality ... See more keywords