CD153 combats Mtb infection
Sign Up to like & getrecommendations! Published in 2018 at "Nature Immunology"
DOI: 10.1038/s41590-018-0246-4
Abstract: Microbial metabolites such as short-chain fatty acids and aryl hydrocarbon receptor ligands shape host metabolism and immune functions. In Immunity, Macpherson and colleagues use stable isotope tracing of microbial and host metabolites to investigate the… read more here.
Keywords: cd153 combats; mtb infection; bacterial metabolites; host ... See more keywords
Viperin impairs the innate immune response through the IRAK1-TRAF6-TAK1 axis to promote Mtb infection
Sign Up to like & getrecommendations! Published in 2022 at "Science Signaling"
DOI: 10.1126/scisignal.abe1621
Abstract: Mycobacterium tuberculosis (Mtb) infection is a long-standing public health threat, and the development of host-directed therapy for eradicating Mtb infection requires better insights into Mtb-host interactions. Viperin [virus-inhibitory protein, endoplasmic reticulum–associated, interferon (IFN) inducible] is… read more here.
Keywords: mtb infection; infection; innate immune; response ... See more keywords
The cGAS/STING Pathway Is Important for Dendritic Cell Activation but Is Not Essential to Induce Protective Immunity against Mycobacterium tuberculosis Infection
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Innate Immunity"
DOI: 10.1159/000488952
Abstract: Mycobacterium tuberculosis (Mtb) infection remains a major public health concern. The STING (stimulator of interferon genes) pathway contributes to the cytosolic surveillance of host cells. Most studies on the role of STING activation in Mtb… read more here.
Keywords: cgas; mtb infection; infection; sting pathway ... See more keywords
Tirap controls Mycobacterium tuberculosis phagosomal acidification
Sign Up to like & getrecommendations! Published in 2023 at "PLOS Pathogens"
DOI: 10.1371/journal.ppat.1011192
Abstract: Progression of tuberculosis is tightly linked to a disordered immune balance, resulting in inability of the host to restrict intracellular bacterial replication and its subsequent dissemination. The immune response is mainly characterized by an orchestrated… read more here.
Keywords: mycobacterium tuberculosis; tuberculosis; tirap; mtb infection ... See more keywords
Overexpression of microRNA-340-5p Ameliorates Inflammatory Response and Intracellular Survival of Mycobacterium Tuberculosis in Alveolar Type II Cells
Sign Up to like & getrecommendations! Published in 2021 at "Infection and Drug Resistance"
DOI: 10.2147/idr.s291867
Abstract: Background The importance of microRNAs (miRs) has been documented in infections. This study estimated the role of miR-340-5p in Mycobacterium tuberculosis (Mtb)-infected alveolar type II cells. Methods The microarray of GEO database was analyzed to… read more here.
Keywords: mycobacterium tuberculosis; mir 340; infection; mtb infection ... See more keywords
Polarization of Human Monocyte-Derived Cells With Vitamin D Promotes Control of Mycobacterium tuberculosis Infection
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2019.03157
Abstract: Background: Understanding macrophage behavior is key to decipher Mycobacterium tuberculosis (Mtb) pathogenesis. We studied the phenotype and ability of human monocyte-derived cells polarized with active vitamin D [1,25(OH)2D3] to control intracellular Mtb infection compared with… read more here.
Keywords: mtb infection; mtb; infection; derived cells ... See more keywords
Mycobacterium tuberculosis Exploits Focal Adhesion Kinase to Induce Necrotic Cell Death and Inhibit Reactive Oxygen Species Production
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.742370
Abstract: Tuberculosis is a deadly, contagious respiratory disease that is caused by the pathogenic bacterium Mycobacterium tuberculosis (Mtb). Mtb is adept at manipulating and evading host immunity by hijacking alveolar macrophages, the first line of defense… read more here.
Keywords: mtb infection; mtb; cell death;
Macrophage: A Cell With Many Faces and Functions in Tuberculosis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.747799
Abstract: Mycobacterium tuberculosis (Mtb) is the causative agent of human tuberculosis (TB) which primarily infects the macrophages. Nearly a quarter of the world’s population is infected latently by Mtb. Only around 5%–10% of those infected develop… read more here.
Keywords: cell; tuberculosis; mtb infection; mtb ... See more keywords
Monkeying around with MAIT Cells: Studying the Role of MAIT Cells in SIV and Mtb Co-Infection
Sign Up to like & getrecommendations! Published in 2021 at "Viruses"
DOI: 10.3390/v13050863
Abstract: There were an estimated 10 million new cases of tuberculosis (TB) disease in 2019. While over 90% of individuals successfully control Mycobacterium tuberculosis (Mtb) infection, which causes TB disease, HIV co-infection often leads to active… read more here.
Keywords: mait cell; mait cells; mtb infection; infection ... See more keywords