Laboratory evaluation of the Anyplex™ II MTB/MDR and MTB/XDR tests based on multiplex real-time PCR and melting-temperature analysis to identify Mycobacterium tuberculosis and drug resistance.
Sign Up to like & getrecommendations! Published in 2017 at "Diagnostic microbiology and infectious disease"
DOI: 10.1016/j.diagmicrobio.2017.08.016
Abstract: We evaluated the performance of two multiplex, real-time PCR tests (Anyplex II MTB/MDR and MTB/XDR; Seegene, Seoul, Korea), designed to detect the Mycobacterium tuberculosis complex (MTC) and drug-resistance mutations associated with isoniazid, rifampicin, fluoroquinolones, and… read more here.
Keywords: mtb xdr; mtb; mtb mdr; anyplex mtb ... See more keywords
Analytical performance of the Xpert MTB/XDR® assay for tuberculosis and expanded resistance detection.
Sign Up to like & getrecommendations! Published in 2021 at "Diagnostic microbiology and infectious disease"
DOI: 10.1016/j.diagmicrobio.2021.115397
Abstract: In a manufacturer-independent laboratory validation study, the Xpert MTB/XDR® assay demonstrated equivalent limit of detection to Xpert MTB/RIF®, detected 100% of tested resistance mutations and showed some utility for resistance detection in strain mixtures. The… read more here.
Keywords: xpert mtb; xdr assay; mtb xdr; resistance detection ... See more keywords
Rapid Detection of Extensive Drug Resistance by Xpert MTB/XDR Optimizes Therapeutic Decision-Making in Rifampin-Resistant Tuberculosis Patients
Sign Up to like & getrecommendations! Published in 2023 at "Journal of Clinical Microbiology"
DOI: 10.1128/jcm.01832-22
Abstract: The Xpert MTB/XDR assay met the critical need for etiologic diagnosis of tuberculosis and rifampin resistance in previous studies. However, its benefits in tailoring the treatment regimen and improving the outcome for patients with rifampin-resistant… read more here.
Keywords: tuberculosis; resistance; mtb xdr; xpert mtb ... See more keywords
New Xpert MTB/XDR: added value and future in the field
Sign Up to like & getrecommendations! Published in 2020 at "European Respiratory Journal"
DOI: 10.1183/13993003.03616-2020
Abstract: The recent launch of the new Xpert MTB/XDR assay (Cepheid Inc., Sunnyvale, CA, USA) by the Foundation for Innovative New Diagnostics [1] was widely welcomed by the tuberculosis (TB) community, given the critical need for… read more here.
Keywords: mtb xdr; new xpert; mtb; xpert mtb ... See more keywords