Endeavors towards transformation of M. tuberculosis thymidylate kinase (MtbTMPK) inhibitors into potential antimycobacterial agents.
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DOI: 10.1016/j.ejmech.2020.112659
Abstract: As the last enzyme in nucleotide synthesis as precursors for DNA replication, thymidylate kinase of M. tuberculosis (MtbTMPK) attracts significant interest as a target in the discovery of new anti-tuberculosis agents. Earlier, we discovered potent MtbTMPK… read more here.
Keywords: antimycobacterial agents; mtbtmpk inhibitors; tuberculosis; thymidylate kinase ... See more keywords