ZBP1 Protects Against mtDNA-Induced Myocardial Inflammation in Failing Hearts
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DOI: 10.1161/circresaha.122.322227
Abstract: Background: Mitochondrial DNA (mtDNA)-induced myocardial inflammation is intimately involved in cardiac remodeling. ZBP1 (Z-DNA binding protein 1) is a pattern recognition receptor positively regulating inflammation in response to mtDNA in inflammatory cells, fibroblasts, and endothelial… read more here.
Keywords: inflammation; mtdna induced; failing hearts; myocardial inflammation ... See more keywords