More Than a Metabolic Enzyme: MTHFD2 as a Novel Target for Anticancer Therapy?
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DOI: 10.3389/fonc.2020.00658
Abstract: The bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase (MTHFD2) is a mitochondrial one-carbon folate metabolic enzyme whose role in cancer was not known until recently. MTHFD2 is highly expressed in embryos and a wide range of tumors but has… read more here.
Keywords: enzyme; novel target; enzyme mthfd2; mthfd2 novel ... See more keywords