Association between MTHFR C677T polymorphism and risk of coronary artery disease in the Chinese population: meta-analysis
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DOI: 10.1007/s00059-021-05087-2
Abstract: Previous studies have investigated the close association between the MTHFR C677T polymorphism and the risk of coronary heart disease (CAD) in the Chinese population. However, the results remain inconclusive. Therefore, this meta-analysis was performed to… read more here.
Keywords: mthfr c677t; c677t polymorphism; polymorphism risk;
Genetic polymorphism of MTHFR C677T with preterm birth and low birth weight susceptibility: a meta-analysis
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DOI: 10.1007/s00404-017-4322-z
Abstract: PurposeThis study aimed at clarifying the association of maternal and neonatal methylenetetrahydrofolate reductase (MTHFR) C677T polymorphisms with preterm birth (PTB) and low birth weight (LBW) susceptibility, respectively.Materials and methodsA systematic search of Embase, Medline, China… read more here.
Keywords: ptb; mthfr c677t; birth; polymorphism ... See more keywords
Association between the MTHFR-C677T isoform and structure of sperm DNA
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DOI: 10.1007/s10815-017-1015-2
Abstract: PurposeThe aim of this study is to evaluate whether the MTHFR contribution to male decreased fertility can be attributable to anomalies in sperm nucleus DNA structure in relation to defective methylation.MethodsThe presence of MTHFR C677T,… read more here.
Keywords: structure; sperm dna; mthfr c677t; mthfr ... See more keywords
Interaction of thrombophilic SNPs in patients with unexplained infertility—multifactor dimensionality reduction (MDR) model analysis
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DOI: 10.1007/s10815-020-01808-4
Abstract: Purpose Our aim was to evaluate the frequency and SNP-SNP interactions between factor V Leiden ( FVL ) G1691A, prothrombin G20210A mutation, and C677T MTHFR and PAI-1 4G/5G gene polymorphisms in female IVF patients with… read more here.
Keywords: patients unexplained; model; analysis; mthfr c677t ... See more keywords
Association between the MTHFR C677T polymorphism, blood folate and vitamin B12 deficiency, and elevated serum total homocysteine in healthy individuals in Yunnan Province, China
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DOI: 10.1016/j.jcma.2016.07.005
Abstract: Background An increased serum total homocysteine (tHcy) concentration is typically associated with genetic defects involved in Hcy metabolism or related nutritional deficiencies. In this study, the combined effects of methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism and… read more here.
Keywords: mthfr c677t; vitamin b12; vitamin; deficiency ... See more keywords
MTHFR C677T and A1298C polymorphisms may contribute to the risk of Parkinson’s disease: A meta-analysis of 19 studies
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DOI: 10.1016/j.neulet.2017.10.060
Abstract: The 5,10-methylenetetrahydrofolate reductase (MTHFR) gene has been reported to be a candidate gene for susceptibility to Parkinson's disease (PD), but results of different studies are conflicting. Here, we conducted a meta-analysis of published case-control studies… read more here.
Keywords: risk; mthfr c677t; analysis; association ... See more keywords
Lack of association between MTHFR C677T Gene polymorphism with alcohol dependence: A meta-analysis of case-control studies
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DOI: 10.1016/j.neulet.2018.06.044
Abstract: Many studies have reported that MTHFR C677T (rs 1801133) polymorphism is associated with the risk of alcohol dependence(AD). However, there are conflicting results regarding this relationship. In this article, we performed a meta-analysis of case-control… read more here.
Keywords: meta analysis; polymorphism; mthfr c677t;
Association analysis of MTHFR (rs1801133 and rs1801131) and MTRR (rs1801394) gene polymorphisms towards the development of hypertension in the Bai population from Yunnan, China.
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DOI: 10.1080/10641963.2023.2206066
Abstract: OBJECTIVE Hypertension is one of the leading causes of human death and disability. MTHFR and MTRR regulate folate metabolism and are closely linked to hypertension, although the relationship is inconsistent among different ethnic groups. The… read more here.
Keywords: hypertension; mthfr c677t; mtrr; mthfr ... See more keywords
Correlation Between the MTHFR C677T Genotype and Coronary Heart Disease in Populations from Gansu, China.
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DOI: 10.1089/dna.2022.0329
Abstract: This study was designed to evaluate the relationship between polymorphisms in the methylenetetrahydrofolate reductase (MTHFR) gene and coronary heart disease (CHD) in populations from the Gansu region of China. The MTHFR C677T polymorphism genotypes from… read more here.
Keywords: heart disease; coronary heart; mthfr c677t; mthfr ... See more keywords
Association between Methylene-Tetrahydrofolate Reductase C677T Polymorphism and Human Immunodeficiency Virus Type 1 Infection in Morocco.
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DOI: 10.1093/labmed/lmac081
Abstract: Human immunodeficiency virus type 1 (HIV-1) infection varies substantially among individuals. One of the factors influencing viral infection is genetic variability. Methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism is a genetic factor that has been correlated with… read more here.
Keywords: polymorphism; mthfr c677t; infection; association ... See more keywords
MTHFR C677T gene polymorphism and the severity of coronary lesions in acute coronary syndrome
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DOI: 10.1097/md.0000000000009044
Abstract: Abstract The association between methylenetetrahydrofolate reductase (MTHFR) C677T polymorphism, circulating levels of homocysteine (Hcy), and the severity of coronary lesion in patients with acute coronary syndrome (ACS) remains unknown. Consecutive ACS patients were included. MTHFR… read more here.
Keywords: coronary lesions; c677t; mthfr c677t; severity coronary ... See more keywords