MTHFR-deficiency Increases Ischemic Damage Through Reduced Neuronal and Astrocytes Viability and Changes in the Cellular Response (P01-020-19).
Sign Up to like & getrecommendations! Published in 2019 at "Current developments in nutrition"
DOI: 10.1093/cdn/nzz028.p01-020-19
Abstract: Objectives Stroke is a leading cause of disability and death world-wide. Increased levels of homocysteine are associated with risk for stroke. Metheylenetetrahydrofolate reductase (MTHFR) generates methyl groups to aid in the metabolism of homocysteine. A… read more here.
Keywords: mice; stroke; damage; mthfr deficiency ... See more keywords
Contribution of Genetic Test to Early Diagnosis of Methylenetetrahydrofolate Reductase (MTHFR) Deficiency: The Experience of a Reference Center in Southern Italy
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DOI: 10.3390/genes14050980
Abstract: Background: the deficiency of 5,10-Methylenetetrahydrofolate reductase (MTHFR) constitutes a rare and severe metabolic disease and is included in most expanded newborn screening (NBS) programs worldwide. Patients with severe MTHFR deficiency develop neurological disorders and premature… read more here.
Keywords: methylenetetrahydrofolate reductase; diagnosis; reductase mthfr; mthfr deficiency ... See more keywords
MTHFR Deficiency: A Potentially Treatable Cause of Adult-Onset Hereditary Spastic Paraparesis
Sign Up to like & getrecommendations! Published in 2022 at "Annals of Indian Academy of Neurology"
DOI: 10.4103/aian.aian_340_21
Abstract: 1. Abbott AL, Paraskevas KI, Kakkos SK, Golledge J, Eckstein H‐H, Diaz‐Sandoval LJ, et al. Systematic review of guidelines for the management of asymptomatic and symptomatic carotid stenosis. Stroke 2015;46:3288‐301. 2. Moreira de Sousa CS,… read more here.
Keywords: neurology; anterior cerebral; mthfr deficiency; azygos anterior ... See more keywords