Association of MTHFR gene polymorphisms with pancreatic cancer: meta-analysis of 17 case–control studies
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Clinical Oncology"
DOI: 10.1007/s10147-019-01571-2
Abstract: Pancreatic cancer (PC) is a seriously malignant tumor with a low 5-year survival rate. The relationship between methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms and PC has been reported by several studies. However, the results were controversial.… read more here.
Keywords: association; analysis; mthfr gene; meta analysis ... See more keywords
The presence of a polymorphism in the maternal MTHFR gene does not correlate with the incidence of embryonic aneuploidy
Sign Up to like & getrecommendations! Published in 2018 at "Fertility and Sterility"
DOI: 10.1016/j.fertnstert.2018.07.429
Abstract: Objective: Methylenetetrahydrofolate reductase (MTHFR) plays an important role in catalyzing the conversion of 5, 10 methylenetetrahydrofolate into 5-methylenetetrahydrofolate, the predominant circulating form of folate in humans. Variations in the sequence of MTHFR gene have been… read more here.
Keywords: aneuploidy; presence polymorphism; mthfr gene; mthfr ... See more keywords
Differential global and MTHFR gene specific methylation patterns in preeclampsia and recurrent miscarriages: A case-control study from North India.
Sign Up to like & getrecommendations! Published in 2019 at "Gene"
DOI: 10.1016/j.gene.2019.04.036
Abstract: AIM The purpose of the present study is to evaluate and understand the association of global and MTHFR gene specific methylation in preeclampsia and recurrent miscarriages in light of MTHFR C677T polymorphism. METHODS The subjects… read more here.
Keywords: methylation; mthfr gene; specific methylation; gene specific ... See more keywords
Genetic variations of MTHFR gene and their association with preterm birth in Korean women.
Sign Up to like & getrecommendations! Published in 2017 at "Medicina"
DOI: 10.1016/j.medici.2018.01.001
Abstract: BACKGROUND AND OBJECTIVE The MTHFR gene encodes the methylenetetrahydrofolate reductase known to be involved in the homocysteine-methionine pathway. It has been reported that the deficiency of MTHFR activity may cause hyperhomocysteinemia which results in adverse… read more here.
Keywords: korean women; preterm birth; birth korean; mthfr gene ... See more keywords
Effect of B9 and B12 vitamin intake on semen parameters and fertility of men with MTHFR polymorphisms
Sign Up to like & getrecommendations! Published in 2017 at "Andrology"
DOI: 10.1111/andr.12351
Abstract: The methylenetetrahydrofolate reductase (MTHFR) gene codes a crucial enzyme which involve in folate metabolism. The effect of MTHFR gene polymorphisms on male fertility status is uncertain and controversial. We evaluated the effect of B vitamin… read more here.
Keywords: mthfr polymorphisms; mthfr gene; men mthfr; semen parameters ... See more keywords
P42 Association of c677t polymorphism of mthfr gene with hemostasis changes in adolescents with essential hypertension
Sign Up to like & getrecommendations! Published in 2017 at "Archives of Disease in Childhood"
DOI: 10.1136/archdischild-2017-313273.130
Abstract: Background and aims It is known that thrombosis in adolescents with essential hypertension (EH) are rare, however pro-coagulation hemostatic changes are multifactorial and requires detailed study. One of the risk factors can be C677T polymorphism… read more here.
Keywords: mthfr gene; polymorphism mthfr; group; study ... See more keywords
Association of MTHFR gene C677T polymorphism with pregnancy outcome.
Sign Up to like & getrecommendations! Published in 2023 at "European review for medical and pharmacological sciences"
DOI: 10.26355/eurrev_202301_30868
Abstract: OBJECTIVE The two objectives of the present study were to analyze the correlation between pregnancy outcomes and methylenetetrahydrofolate reductase (MTHFR) gene C677T polymorphism, and to provide evidence for clinical improvement of adverse pregnancy outcomes. PATIENTS… read more here.
Keywords: mthfr gene; group; gene c677t; pregnancy ... See more keywords
Identification of SNPs associated with methotrexate treatment outcomes in patients with early rheumatoid arthritis
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.1075603
Abstract: Methotrexate is one of the cornerstones of rheumatoid arthritis (RA) therapy. Genetic factors or single nucleotide polymorphisms (SNPs) are responsible for 15%–30% of the variation in drug response. Identification of clinically effective SNP biomarkers for… read more here.
Keywords: outcomes patients; rheumatology; mthfr gene; rheumatoid arthritis ... See more keywords
Effect of interaction between occupational stress and polymorphisms of MTHFR gene and SELE gene on hypertension
Sign Up to like & getrecommendations! Published in 2022 at "PeerJ"
DOI: 10.7717/peerj.12914
Abstract: Background Gene-environment interaction is related to the prevalence of hypertension, but the impact of genetic polymorphisms on hypertension may vary due to different geography and population. Objective To explore the impact of the interaction among… read more here.
Keywords: interaction; mthfr gene; hypertension; occupational stress ... See more keywords