Design of Montelukast Nanocrystalline Suspension for Parenteral Prolonged Delivery
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Nanomedicine"
DOI: 10.2147/ijn.s375888
Abstract: Background Montelukast (MTK), a representative leukotriene receptor antagonist, is currently being investigated as a potential candidate for treating Alzheimer’s disease. For potent and effective dosing in elderly patients, a parenteral prolonged delivery system is favored,… read more here.
Keywords: nanocrystalline suspension; prolonged delivery; mtk; delivery ... See more keywords
Montelukast Nanocrystals for Transdermal Delivery with Improved Chemical Stability
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DOI: 10.3390/pharmaceutics12010018
Abstract: A novel nanocrystal system of montelukast (MTK) was designed to improve the transdermal delivery, while ensuring chemical stability of the labile compound. MTK nanocrystal suspension was fabricated using acid-base neutralization and ultra-sonication technique and was… read more here.
Keywords: transdermal delivery; delivery; chemical stability; drug ... See more keywords
Improved Bioavailability of Montelukast through a Novel Oral Mucoadhesive Film in Humans and Mice
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DOI: 10.3390/pharmaceutics13010012
Abstract: The leukotriene receptor antagonist Montelukast (MTK) is an approved medication for the treatment of asthma and allergic rhinitis. The existing marketed tablet forms of MTK exhibit inconsistent uptake and bioavailability, which partially explains the presence… read more here.
Keywords: mucoadhesive film; improved bioavailability; film; montelukast ... See more keywords