WAVE2 suppresses mTOR activation to maintain T cell homeostasis and prevent autoimmunity
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DOI: 10.1126/science.aaz4544
Abstract: WAVE-ing T cell activation off The WAVE regulatory complex (WRC) is a pentameric complex that regulates actin cytoskeleton dynamics. The precise role for the WRC in immunity has not been established, although recent work has… read more here.
Keywords: wave2; mtor; mtor activation; mice ... See more keywords