Articles with "mtor hdacs" as a keyword



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Design, synthesis and biological evaluation of novel hybrids targeting mTOR and HDACs for potential treatment of hepatocellular carcinoma.

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Published in 2021 at "European journal of medicinal chemistry"

DOI: 10.1016/j.ejmech.2021.113824

Abstract: Hepatocellular carcinoma (HCC) is a major contributor to global cancer incidence and mortality. Many pathways are involved in the development of HCC and various proteins including mTOR and HDACs have been identified as potential drug… read more here.

Keywords: hepatocellular carcinoma; treatment; hdacs; mtor hdacs ... See more keywords