The Role of Autophagy for the Regeneration of the Aging Liver
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DOI: 10.3390/ijms21103606
Abstract: Age is one of the key risk factors to develop malignant diseases leading to a high incidence of hepatic tumors in the elderly population. The only curative treatment for hepatic tumors is surgical removal, which… read more here.
Keywords: liver regeneration; regeneration; autophagy via; mtor independent ... See more keywords
PTEN negatively regulates the cell lineage progression from NG2+ glial progenitor to oligodendrocyte via mTOR-independent signaling
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DOI: 10.7554/elife.32021
Abstract: Oligodendrocytes (OLs), the myelin-forming CNS glia, are highly vulnerable to cellular stresses, and a severe myelin loss underlies numerous CNS disorders. Expedited OL regeneration may prevent further axonal damage and facilitate functional CNS repair. Although… read more here.
Keywords: pten negatively; mtor independent; regeneration; negatively regulates ... See more keywords