Caralluma pauciflora based Ag-NPs activate ROS - induced apoptosis through down-regulation of AKT, mTOR and pI3K signaling in human gastric cancer (AGS) cells
Sign Up to like & getrecommendations! Published in 2024 at "Nanotechnology"
DOI: 10.1088/1361-6528/ad26d9
Abstract: The phytochemicals found in Caralluma pauciflora were studied for their ability to reduce silver nitrate in order to synthesise silver nanoparticles (AgNPs) and characterise their size and crystal structure. Thunbergol, 1,1,6-trimethyl-3-methylene-2-(3,6,9,13-tetram, Methyl nonadecanoate, Methyl cis-13,16-Docosadienate,… read more here.
Keywords: cancer; caralluma pauciflora; akt mtor; gastric cancer ... See more keywords
Abstract 7036: Co-targeting AR, mTOR, and PI3K inhibitors in DSRCT as a novel therapeutic approach
Sign Up to like & getrecommendations! Published in 2025 at "Cancer Research"
DOI: 10.1158/1538-7445.am2025-7036
Abstract: DSRCT (Desmoplastic Small Round Cell Tumor) is a rare soft tissue sarcoma that appears in the abdominal and pelvic area of mainly young males. There is little information about the molecular mechanisms involved in its… read more here.
Keywords: cancer; targeting mtor; pi3k mtor; mtor ... See more keywords
Reduced lncRNA Aim enhances the malignant invasion of triple-negative breast cancer cells mainly by activating Wnt/β-catenin/mTOR/PI3K signaling.
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DOI: 10.1691/ph.2017.7547
Abstract: Increasing evidence has suggested the important role of lncRNAs in the progression of triple-negative breast cancer (TNBC). In the current study, we first demonstrated that the expression of Airn was reduced in TNBC tissues and… read more here.
Keywords: catenin mtor; mtor pi3k; wnt catenin; mda 231 ... See more keywords