Sphingomyelin in microdomains of the plasma membrane regulates amino acid‐stimulated mTOR signal activation
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DOI: 10.1002/cbin.10941
Abstract: Sphingomyelin (SM) is required for cells to proliferate, but the reason is not fully understood. In order to asses this question, we employed a cell line, ZS, which lacks both SMS1 and SMS2, isolated from… read more here.
Keywords: amino acid; stimulated mtor; mtor; mtor signal ... See more keywords
mTOR Signal Pathway Inhibition Promote the Cytotoxicity of Chemotherapy on SHI-1 Cells
Sign Up to like & getrecommendations! Published in 2019 at "Blood"
DOI: 10.1182/blood-2019-126714
Abstract: Acute myeloid leukemia (AML) is a malignant hematologic disorder. Although current chemotherapy could improve the survival rate of AML patients, some patient would suffer from relapse and had bad therapeutic response. Nowadays, many studies have… read more here.
Keywords: chemotherapy; group; signal pathway; mtor signal ... See more keywords