mTORC1-independent autophagy regulates receptor tyrosine kinase phosphorylation in colorectal cancer cells via an mTORC2-mediated mechanism
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DOI: 10.1038/cdd.2017.41
Abstract: The intracellular autophagic degradative pathway can have a tumour suppressive or tumour-promoting role depending on the stage of tumour development. Upon starvation or targeting of oncogenic receptor tyrosine kinases (RTKs), autophagy is activated owing to… read more here.
Keywords: receptor tyrosine; autophagy; cancer cells; cancer ... See more keywords