Articles with "mtorc1 rps15" as a keyword



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mTORC1-Rps15 Axis Contributes to the Mechanisms Underlying Global Translation Reduction During Senescence of Mouse Embryonic Fibroblasts

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Published in 2019 at "Frontiers in Cell and Developmental Biology"

DOI: 10.3389/fcell.2019.00337

Abstract: The reduction of protein translation is a common feature in senescent cells and aging organisms, yet the underlying mechanisms are not fully understood. Here we show that both global mRNA translation and mammalian/mechanistic target of… read more here.

Keywords: embryonic fibroblasts; senescence; rps15 axis; translation ... See more keywords