Venlafaxine protects against chronic stress-related behaviors in mice by activating the mTORC1 signaling cascade.
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DOI: 10.1016/j.jad.2020.07.096
Abstract: BACKGROUND Recent studies have suggested the role of mammalian target of rapamycin complex 1 (mTORC1) in the pathophysiology of depression. Although venlafaxine was thought to be a serotonin and norepinephrine reuptake inhibitor (SNRI), its pharmacological… read more here.
Keywords: mtorc1 signaling; venlafaxine; mtorc1 system; mtorc1 ... See more keywords