CD146 Regulates Growth Factor-Induced mTORC2 Activity Independent of the PI3K and mTORC1 Pathways.
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DOI: 10.1016/j.celrep.2019.09.047
Abstract: The mechanistic target of rapamycin complex 2 (mTORC2) coordinates cell proliferation, survival, and metabolism with environmental inputs, yet how extracellular stimuli such as growth factors (GFs) activate mTORC2 remains enigmatic. Here we demonstrate that in… read more here.
Keywords: mtorc2 activity; cd146; mtorc1 pathways; pi3k mtorc1 ... See more keywords