mTORC2/Akt activation in adipocytes is required for adipose tissue inflammation in tuberculosis
Sign Up to like & getrecommendations! Published in 2019 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2019.06.052
Abstract: Background Mycobacterium tuberculosis has co-evolved with the human host, adapting to exploit the immune system for persistence and transmission. While immunity to tuberculosis (TB) has been intensively studied in the lung and lymphoid system, little… read more here.
Keywords: tuberculosis; mtorc2 akt; adipose tissue; tissue inflammation ... See more keywords
PINK1 ameliorates acute-on-chronic liver failure by inhibiting apoptosis through mTORC2/AKT signaling
Sign Up to like & getrecommendations! Published in 2022 at "Cell Death Discovery"
DOI: 10.1038/s41420-022-01021-5
Abstract: Acute-on-chronic liver failure (ACLF) is a lethal syndrome with a remarkable short-term death rate. Even worse, effective internal medicine therapies are currently lacking. Increasing evidence indicates apoptosis plays a critical role in the progression of… read more here.
Keywords: liver failure; apoptosis; pink1; mtorc2 akt ... See more keywords
mTORC2-AKT-LAT1 Signalling Participates in Methionine-induced β-CASEIN Expression in Mammary Epithelial Cells of Dairy Cows.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of animal physiology and animal nutrition"
DOI: 10.1111/jpn.13819
Abstract: This study investigated the role of the mammalian target of rapamycin complex 2 (mTORC2)-protein kinase B (AKT) signalling in methionine (Met)-induced L-type amino acid transporter 1 (LAT1) expression and milk protein production. Primary mammary epithelial… read more here.
Keywords: induced casein; met induced; expression; lat1 expression ... See more keywords
ITGB1 Suppresses Autophagy Through Inhibiting The mTORC2/AKT Signaling Pathway In H9C2 Cells.
Sign Up to like & getrecommendations! Published in 2022 at "Die Pharmazie"
DOI: 10.1691/ph.2022.2351
Abstract: Cardiomyocyte autophagy is closely related to myocardial infarction and hypertrophy. To study the molecular mechanism of autophagy is helpful for the prevention and treatment of these diseases. As a cell surface receptor, the function of… read more here.
Keywords: itgb1; h9c2 cells; mtorc2 akt; autophagy ... See more keywords