Articles with "mtr3d" as a keyword



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MTR3D: identifying regions within protein tertiary structures under purifying selection

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Published in 2021 at "Nucleic Acids Research"

DOI: 10.1093/nar/gkab428

Abstract: Abstract The identification of disease-causal variants is non-trivial. By mapping population variation from over 448,000 exome and genome sequences to over 81,000 experimental structures and homology models of the human proteome, we have calculated both… read more here.

Keywords: protein; mtr3d; variation; missense ... See more keywords