Global mapping of MtrA-binding sites links MtrA to regulation of its targets in Mycobacterium tuberculosis.
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DOI: 10.1099/mic.0.000585
Abstract: Mycobacterium tuberculosis employs two-component systems (TCSs) for survival within its host. The TCS MtrAB is conserved among mycobacteria. The response regulator MtrA is essential in M. tuberculosis. The genome-wide chromatin immunoprecipitation (ChIP) sequencing performed in… read more here.
Keywords: tuberculosis; expression; mtra binding; global mapping ... See more keywords