Mirtazapine loaded polymeric micelles for rapid release tablet: A novel formulation—In vitro and in vivo studies
Sign Up to like & getrecommendations! Published in 2024 at "Drug Delivery and Translational Research"
DOI: 10.1007/s13346-024-01525-w
Abstract: Major depression is a prevalent disorder characterized by sadness, lack of interest or pleasure, interrupted sleep or food, and impaired concentration. Mirtazapine (MTZ), a tetracyclic antidepressant drug, is commonly used to treat moderate to severe… read more here.
Keywords: polymeric micelles; vitro; mtz pms; tablet ... See more keywords
Is there a big mantle wedge under eastern Tibet?
Sign Up to like & getrecommendations! Published in 2019 at "Physics of the Earth and Planetary Interiors"
DOI: 10.1016/j.pepi.2019.04.005
Abstract: Abstract The big mantle wedge (BMW) model was originally proposed to explain the origin of the intraplate Changbaishan volcano in NE China where the subducting Pacific slab becomes stagnant in the lower part of the… read more here.
Keywords: mantle; eastern tibet; mtz; big mantle ... See more keywords
Thermocatalytic persulfate activation for metronidazole removal in the continuous operation
Sign Up to like & getrecommendations! Published in 2021 at "Separation and Purification Technology"
DOI: 10.1016/j.seppur.2020.118055
Abstract: Abstract In the present study, thermocatalytic persulfate (PS) activation using zero-valent copper was studied under different conditions to investigate the degradation of metronidazole (MTZ) antibiotic from aqueous media in the continuous system. The results showed… read more here.
Keywords: thermocatalytic persulfate; mtz; continuous operation; activation ... See more keywords
Molecular Mechanism of Unexpected Metal-Independent Hydroxyl Radical Production by Mercaptotriazole and H2O2.
Sign Up to like & getrecommendations! Published in 2025 at "Environmental science & technology"
DOI: 10.1021/acs.est.3c10806
Abstract: It is well known that hydroxyl radical (·OH) can be largely produced either through the classic iron-mediated inorganic-Fenton system or our recently discovered haloquinones/H2O2 organic-Fenton-like system, but rarely produced via thiol compounds. Here, unexpectedly, we… read more here.
Keywords: hydroxyl radical; h2o2; thiol compounds; mercaptotriazole ... See more keywords
Pharmacokinetic and Pharmacodynamic Effects of Metronidazole May Account for the Superior Efficacy of Multidose Therapy Among Women With Trichomoniasis.
Sign Up to like & getrecommendations! Published in 2019 at "Sexually Transmitted Diseases"
DOI: 10.1097/olq.0000000000001059
Abstract: P resently, the Centers for Disease Control and Prevention and the World Health Organization recommend 2 g of metronidazole (MTZ) in a single dose for the treatment of trichomoniasis in women. For over three decades,… read more here.
Keywords: may account; single dose; mtz; treatment failure ... See more keywords
Diversity, species richness distribution and centers of endemism of Lycianthes (Capsiceae, Solanaceae) in Mexico
Sign Up to like & getrecommendations! Published in 2021 at "Phytotaxa"
DOI: 10.11646/phytotaxa.514.1.3
Abstract: Spatial patterns of plant diversity matter. Identifying areas of high species richness and endemism are crucial for understanding the evolution of plant diversity and community assemblages as well establishing sustainablility and conservation priorities. Lycianthes is… read more here.
Keywords: diversity; endemism; mtz; species richness ... See more keywords
Genetic basis for metronidazole and clarithromycin resistance in Helicobacter pylori strains isolated from patients with gastroduodenal disorders
Sign Up to like & getrecommendations! Published in 2019 at "Infection and Drug Resistance"
DOI: 10.2147/idr.s192942
Abstract: Background The aim of this study was to evaluate the antimicrobial resistance and genetic basis for metronidazole (Mtz) and clarithromycin (Cla) resistance in strains of Helicobacter pylori, isolated from patients with gastroduodenal disorders. Patients and… read more here.
Keywords: resistant strains; mtz; genetic basis; resistance ... See more keywords
Methazolamide Attenuates the Development of Diabetic Cardiomyopathy by Promoting β-Catenin Degradation in Type 1 Diabetic Mice.
Sign Up to like & getrecommendations! Published in 2022 at "Diabetes"
DOI: 10.2337/db21-0506
Abstract: Methazolamide (MTZ), a carbonic anhydrase inhibitor, has been shown to inhibit cardiomyocyte hypertrophy and exert a hypoglycemic effect in patients with type 2 diabetes mellitus and diabetic db/db mice. However, whether MTZ has a cardioprotective… read more here.
Keywords: diabetic mice; mtz; degradation; catenin ... See more keywords
Genotoxicity from metronidazole detected in vitro, but not in vivo, in healthy dogs in a randomized clinical trial.
Sign Up to like & getrecommendations! Published in 2022 at "American journal of veterinary research"
DOI: 10.2460/ajvr.22.07.0112
Abstract: OBJECTIVE To determine whether metronidazole (MTZ), at recommended therapeutic dosages in dogs, induces peripheral blood cell (PMBC) genotoxicity, using the γ-H2AX assay as a sensitive measure of DNA breaks. The secondary aim was to assess… read more here.
Keywords: healthy dogs; dna; vivo healthy; mtz ... See more keywords
The MtZ Strain: Molecular Characteristics and Outbreak Investigation of the Most Successful Mycobacterium tuberculosis Strain in Aragon Using Whole-Genome Sequencing
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2022.887134
Abstract: Since 2004, a tuberculosis surveillance protocol has been carried out in Aragon, thereby managing to detect all tuberculosis outbreaks that take place in the community. The largest outbreak was caused by a strain named Mycobacterium… read more here.
Keywords: mycobacterium tuberculosis; strain; genome; molecular characteristics ... See more keywords
Evaluation of Metronidazole Resistance of Vaginal Swab Isolates from South African Women Treated for Bacterial Vaginosis
Sign Up to like & getrecommendations! Published in 2024 at "Antibiotics"
DOI: 10.3390/antibiotics13121217
Abstract: Background/Objectives: The high recurrence rate of bacterial vaginosis (BV) after antibiotic treatment is at least partially attributed to resistant bacteria. The CAPRISA 083 (CAP083) study investigated the influence of metronidazole (MTZ) treatment on the vaginal… read more here.
Keywords: gardnerella; resistance; treatment; bacterial vaginosis ... See more keywords