Enhanced Manipulation of Human Mitochondrial DNA Heteroplasmy In Vitro Using Tunable mtZFN Technology.
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DOI: 10.1007/978-1-4939-8799-3_4
Abstract: As a platform capable of mtDNA heteroplasmy manipulation, mitochondrially targeted zinc-finger nuclease (mtZFN) technology holds significant potential for the future of mitochondrial genome engineering, in both laboratory and clinic. Recent work highlights the importance of… read more here.
Keywords: mtzfn technology; heteroplasmy; mtzfn; enhanced manipulation ... See more keywords