Pseudomonas aeruginosa increases MUC1 expression in macrophages through the TLR4-p38 pathway.
Sign Up to like & getrecommendations! Published in 2017 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2017.08.056
Abstract: Alveolar macrophages (AMs) play a critical role in the clearance of Pseudomonas aeruginosa (Pa) from the airways. However, hyper-activation of macrophages can impair bacterial clearance and contribute to morbidity and mortality. MUC1 mucin is a… read more here.
Keywords: expression macrophages; pseudomonas aeruginosa; muc1 expression; tlr4 p38 ... See more keywords
Activation of Vitamin D/VDR Signaling Reverses Gemcitabine Resistance of Pancreatic Cancer Cells Through Inhibition of MUC1 Expression.
Sign Up to like & getrecommendations! Published in 2022 at "Digestive diseases and sciences"
DOI: 10.1158/1538-7445.am2022-6367
Abstract: BACKGROUND Pancreatic ductal adenocarcinoma (PDA) has a poor prognosis due to its therapeutic resistance. Inactivation of vitamin D/vitamin D receptor (VDR) signaling may contribute to the malignant phenotype of PDA and altered expression of oncoprotein… read more here.
Keywords: vitamin vdr; expression; resistance; vdr signaling ... See more keywords
Mucin 1 expression is regulated by hsa_circ_0055054/microRNA‑122‑5p and promotes hepatocellular carcinoma development
Sign Up to like & getrecommendations! Published in 2024 at "Oncology Letters"
DOI: 10.3892/ol.2024.14537
Abstract: The abnormal expression of mucin 1 (MUC1) is a major cause of poor prognosis in patients with hepatocellular carcinoma (HCC). Competitive endogenous RNA demonstrates a novel regulatory mechanism that can affect the biological behavior of… read more here.
Keywords: circ 0055054; hsa circ; muc1 expression; circ ... See more keywords