MUC13 protects colorectal cancer cells from death by activating the NF-κB pathway and is a potential therapeutic target
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DOI: 10.1038/onc.2016.241
Abstract: MUC13 is a transmembrane mucin glycoprotein that is over produced by many cancers, although its functions are not fully understood. Nuclear factor-κB (NF-κB) is a key transcription factor promoting cancer cell survival, but therapeutically targeting… read more here.
Keywords: death; colorectal cancer; muc13; activation ... See more keywords
Abstract 198: MUC13 promotes pancreatic tumor-stromal interactions by influencing tumor microenvironment
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Research"
DOI: 10.1158/1538-7445.am2018-198
Abstract: Objective: Pancreatic cancer (PanCa) is the third leading cause of cancer-related deaths in the U.S. MUC13, mucin, is aberrantly expressed in PanCa and its overexpression leads to tumorigenic and metastatic behavior of cancer cells. Herein,… read more here.
Keywords: muc13; resistance; cancer; tumor microenvironment ... See more keywords
Reduction of miR-132-3p contributes to gastric cancer proliferation by targeting MUC13
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DOI: 10.3892/mmr.2017.6347
Abstract: Abnormal expression of epidermal growth factor receptor (EGFR) signaling and microRNAs (miRNAs) has been widely seen in gastric cancer. The present study focused on the miRNAs that regulate human epidermal growth factor receptor (HER) activation… read more here.
Keywords: mir 132; gastric cancer; muc13; reduction mir ... See more keywords