MUC21 controls melanoma progression via regulating SLITRK5 and hedgehog signaling pathway
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DOI: 10.1002/cbin.11817
Abstract: Mucins are heavily glycosylated proteins secreted by various cell types, to protect the epithelial surface of the gastrointestinal tract from damage. Currently, increasing studies provided evidence to suggest that mucins play an essential role in… read more here.
Keywords: muc21; hedgehog; progression; melanoma progression ... See more keywords
Mucin 21 confers resistance to apoptosis in an O-glycosylation-dependent manner
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DOI: 10.1038/s41420-022-01006-4
Abstract: Highly glycosylated mucins protect epithelial surfaces from external insults and are related to malignant behaviors of carcinoma cells. However, the importance of carbohydrate chains on mucins in the process of cellular protection is not fully… read more here.
Keywords: mucin; glycosylation; resistance; apoptosis ... See more keywords